Publications by authors named "Ana M Lyons"
Article Synopsis
- - The study evaluated the performance of ten quick lateral flow assays and two lab-based tests for detecting antibodies against SARS-CoV-2, focusing on the time after symptom onset and previous test samples.
- - It found that seropositivity increased over time, peaking over 20 days after symptoms began, but test specificity varied between 84.3% and 100%, mainly influenced by IgM results.
- - Recommendations from the study emphasize optimizing seropositivity thresholds and ensuring proper reader training to improve the reliability of these assays, with four tests showing over 80% positivity and over 95% specificity in later time intervals.
Background: Serological tests are crucial tools for assessments of SARS-CoV-2 exposure, infection and potential immunity. Their appropriate use and interpretation require accurate assay performance data.
Method: We conducted an evaluation of 10 lateral flow assays (LFAs) and two ELISAs to detect anti-SARS-CoV-2 antibodies.
Adaptive impact of the chimeric gene Quetzalcoatl in Drosophila melanogaster.
Proc Natl Acad Sci U S A
June 2010
Chimeric genes, which form through the genomic fusion of two protein-coding genes, are a significant source of evolutionary novelty in Drosophila melanogaster. However, the propensity of chimeric genes to produce adaptive phenotypic changes is not fully understood. Here, we describe the chimeric gene Quetzalcoatl (Qtzl; CG31864), which formed in the recent past and swept to fixation in D.
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