Parenting stress in parents of children with developmental coordination disorder.

Background: Developmental Coordination Disorder (DCD) is a neurodevelopmental disorder which affects around 5% of children but is often not detected by clinicians.

Aims: The aim of the current study was to investigate whether parents of children with DCD report clinically-significant levels of parenting stress, and to assess a number of factors contributing to this stress, based on evidence from research into other neurodevelopmental disorders.

Methods And Procedures: A survey was completed by 174 parents of children aged 5-12 years with DCD (parents age M = 42;3, SD = 4;11), comprising measures of the child's motor difficulties and behavioural problems, the parent's perceived competence in the parenting role and perceived levels of social support, and parenting stress.

Research Review: Internalising symptoms in developmental coordination disorder: a systematic review and meta-analysis.

Background: Developmental coordination disorder (DCD) affects 5%-6% of children. There is growing evidence that DCD is associated with greater levels of internalising symptoms (i.e.

Central neuropeptide Y modulates binge-like ethanol drinking in C57BL/6J mice via Y1 and Y2 receptors.

Frequent binge drinking has been linked to heart disease, high blood pressure, type 2 diabetes, and the development of ethanol dependence. Thus, identifying pharmaceutical targets to treat binge drinking is of paramount importance. Here we employed a mouse model of binge-like ethanol drinking to study the role of neuropeptide Y (NPY).

Chronic stress alters neuropeptide Y signaling in the bed nucleus of the stria terminalis in DBA/2J but not C57BL/6J mice.

Numerous rodent and human studies have demonstrated that neuropeptide Y (NPY) is involved in the regulation of anxiety-related behaviors. In this study, we examined whether there were differences in NPY signaling between two inbred mouse strains (C57BL/6J and DBA/2J) that exhibit divergent basal and stress-induced anxiety phenotypes. We focused on the bed nucleus of the stria terminals (BNST), a structure in the extended amygdala that is important for the regulation of anxiety-like behavior and contains NPY receptors.