Bisphenol A (BPA) is a widely used plasticizer agent and a well-known ubiquitous endocrine disruptor, which is frequently associated with a series of reproductive, developmental, and transgenerational effects over wildlife, livestocks, and humans. Although extensive toxicological data is available for metazoans, the impact of BPA over unicellular eukaryotes, which represents a considerable proportion of eukaryotic diversity, remains largely overlooked. Here, we used acute end-point toxicological assay and an inverted virtual-screening (IVS) approach to evaluate cellular impairments infringed by BPA over the cosmopolitan ciliated protist, Paramecium caudatum.
View Article and Find Full Text PDFEnviron Toxicol Pharmacol
July 2021
Female juveniles of the Neotropical fish Astyanax altiparanae were exposed for 96 h to four treatments containing the active ingredient from Imidacloprid® commercial formulation (IMI 1, IMI 2, IMI 3, and IMI 4) and to a control treatment (only dechlorinated tap water). Glutathione content, glutathione S-transferase activity, lipid peroxidation (LPO) and protein carbonylation levels, acetylcholinesterase (AChE) activity, and frequency of micronuclei and erythrocyte nuclear abnormalities (ENA) were measured in the fish. The muscle and gills were the most affected organs; their antioxidant defense was not enough to prevent oxidative damage (LPO) in the IMI 2 and IMI 4 treatment fish.
View Article and Find Full Text PDFEcotoxicol Environ Saf
October 2020
Cyanobacteria have been considered a major global threat because of their widespread ability to proliferate and contaminate inland and marine waters with toxic metabolites. For this reason, to avoid risks to humans and environmental health, regulatory legislation and guidelines have been established based on extensive toxicological data. However, most of what is known in this field come from works on microcystin (MC) variants, which effects were almost exclusively tested in metazoan models.
View Article and Find Full Text PDFEnviron Sci Pollut Res Int
September 2019
Aside from the ability of plants to remove domestic-industrial wastewater contaminants from various types of water, macrophytes can also serve as an alternative source of energy. The goal of the present study was to test the viability of biogas production using aquatic macrophyte species-Eichhornia crassipes and Pistia stratiotes-contaminated with cadmium (Cd) after the phytoremediation process. The plants were transferred to a nutrient solution contaminated with 0.
View Article and Find Full Text PDFThe Funil Reservoir (Rio de Janeiro State, Brazil) is an environment degraded by constant discharge of nutrients and pollution coming from the most industrialized region of the country. As a consequence of eutrophication, there are continuous cyanobacteria blooms, which cause acute and chronic toxicity to zooplankton. In this context, Phase I of Toxicity Identification Evaluation (TIE) was performed on Daphnia similis using water and interstitial water from the reservoir, with the aim of identifying classes of compounds responsible for toxicity.
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