Publications by authors named "Ana Lucia Acquesta"
Article Synopsis
- The study aimed to compare the effectiveness of T-piece resuscitators versus self-inflating bags for ventilating preterm infants at birth, focusing on survival rates without major health issues by discharge.
- Conducted in 20 Brazilian hospitals with 1962 infants born between 23-33 weeks of gestation, the research followed standardized ventilation guidelines and adjustable logistic regression for outcomes.
- Results showed that infants ventilated with T-piece resuscitators had a higher survival rate (47%) without significant complications compared to those using self-inflating bags (35%), indicating that the T-piece may improve neonatal outcomes.
Objective: To apply, in Brazil, the T-cell receptor excision circles (TRECs) quantification technique using real-time polymerase chain reaction in newborn screening for severe combined immunodeficiency and assess the feasibility of implementing it on a large scale in Brazil.
Methods: 8715 newborn blood samples were collected on filter paper and, after DNA elution, TRECs were quantified by real-time polymerase chain reaction. The cutoff value to determine whether a sample was abnormal was determined by ROC curve analysis, using SSPS.
Objective: To analyze unfavorable outcomes at hospital discharge of preterm infants born at Brazilian public university centers.
Methods: Prospective cohort of 2646 inborn infants with gestational age 23-33 weeks and birth weight 400-1499 g, without malformations, born at 20 centers in 2012-2013. Unfavorable outcome was defined as in-hospital death or survival at hospital discharge with ≥1 major morbidities: bronchopulmonary dysplasia (BPD) at 36 corrected weeks, intraventricular hemorrhage (IVH) grades 3-4, periventricular leukomalacia (PVL) or surgically treated retinopathy of prematurity (ROP).