Women faculty members' challenges when pursuing leadership positions in academic dentistry: A survey.

Purpose/objectives: This study addresses persistent gender disparities in leadership roles in academic dentistry. The objectives were to identify the challenges and barriers to leadership that women face in general and during the COVID-19 pandemic, as well as to describe resources they need to reach their leadership potential.

Methods: The American Dental Education Association Section on Women in Leadership (WIL), gathered survey data concerning leadership challenges and faculty development needs.

Reconstruction of penile skin defect using negative pressure therapy, spiraling full-thickness skin grafts, and nanofat grafting: a case report.

The penis is a structure that requires both anatomical and functional reconstruction. Being a three-dimensional structure that changes in volume, it presents a reconstructive challenge for the plastic surgeon. Currently, various alternatives are available for covering these complex defects, such as grafts, flaps, and dermal matrices.

Hydrogen peroxide diffusion across the red blood cell membrane occurs mainly by simple diffusion through the lipid fraction.

Hydrogen peroxide (HO) is an oxidant produced endogenously by several enzymatic pathways. While it can cause molecular damage, HO also plays a role in regulating cell proliferation and survival through redox signaling pathways. In the vascular system, red blood cells (RBCs) are notably efficient at metabolizing HO.

Evaluation of asbestos dispersion during laser ablation of rocks containing Naturally Occurring Asbestos (NOA).

Health risks are often overlooked when the short-term consequences are not immediately apparent. During restoration work, cleaning actions can generate particles that pose health risks to workers through inhalation. This is particularly true in the case of asbestos fibres that might be spread out from the laser cleaning of buildings or heritage artifacts made of stone, such as serpentinite and other ultramafic rocks, that have a high probability of containing asbestos (e.

Analysis of household waste production in Ecuador: Limitations for sustainable management in local communities.

Municipal solid waste management is one of the greatest challenges for environmental sustainability and well-being in developing countries, where the infrastructure and financial resources required to carry out such services are often lacking. The design of solutions that adequately respond to local needs must be based on quality information about the quantity and composition of the generated waste and current management practices. This study evaluated domestic waste generation and its management in 81 communities in Ecuador based on sampling at the source and population surveys.

Pericapsular nerve group block: a 3D CT scan imaging study to determine the spread of injectate.

Background: Current understanding of the mechanism of action of the pericapsular nerve group (PENG) block is primarily based on cadaver studies. We performed an imaging study in patients undergoing hip surgery to enhance the understanding of the analgesic mechanisms following a PENG block.

Materials And Methods: 10 patients scheduled for hip surgery received an ultrasound-guided PENG block with 18 mL of 0.

SEOM-GEMCAD-TTD clinical guidelines for the management of hepatocarcinoma patients (2023).

Hepatocellular carcinoma (HCC) is the most common primary malignancy in the liver and is the third cause of cancer-related death worldwide. Surveillance with abdominal ultrasound should be offered to individuals at high risk for developing HCC. Accurate diagnosis, staging, and liver function are crucial when determining the optimal therapeutic approach.

Therapists to Therapy Assistants: Experiences of Internationally Educated Physiotherapists and Occupational Therapists.

In Canada, internationally educated physiotherapists (IEPTs) and occupational therapists (IEOTs) may work as occupational/physical therapy assistants (OTAs/PTAs) while pursuing Canadian licensure. This experience presents personal and professional opportunities and challenges. We explored a) the barriers and facilitators experienced by IEPTs and IEOTs working as OTAs/PTAs while pursuing licensure in Canada and b) how might their professional identity changes during this period.

The role of time to positive blood cultures in enhancing the predictive capability of DENOVA score for diagnosing infective endocarditis in patients with Enterococcus faecalis bacteremia.

DENOVA-score is useful to stratify the risk of infective endocarditis (IE) in Enterococcus faecalis bacteremia. Recently, time to positive (TTP) of blood cultures has also been related with a higher risk of IE. The objective was to evaluate DENOVA- score with TTP to improve its specificity.

Preventing alpelisib-related hyperglycaemia in HR+/HER2-/-mutated advanced breast cancer using metformin (METALLICA): a multicentre, open-label, single-arm, phase 2 trial.

Background: Hyperglycaemia is an early and frequent adverse event during alpelisib treatment. METALLICA aimed to evaluate prophylactic metformin to prevent or reduce hyperglycaemia occurrence in patients with HR+/HER2-/-mutated advanced breast cancer (ABC).

Methods: Between August 13th, 2020 and March 23rd, 2022, this 2-cohort, phase 2, multicentre, single-arm trial (NCT04300790) enrolled patients with HR+/HER2-/PIK3CA-mutated ABC: cohort A, normal glycaemia (fasting plasma glucose <100 mg/dL [<5.

Identifying Factors Associated With Disparities in Access to Integrative Oncology Program.

Context And Objectives: Cancer centers are increasingly providing complementary medicine as part of an emerging discipline termed 'integrative oncology' (IO). The present study explored factors associated with disparities in referral and adherence to a freely-provided IO program.

Methods: The databases of three oncology centers in northern Israel were searched retrospectively for chemotherapy-treated oncology patients eligible for referral by their oncology healthcare professionals to an integrative physician (IP) consultation.

C-H, N-H, and O-H Bond Activations to Prepare Phosphorescent Hydride-Iridium(III)-Phosphine Emitters with Photocatalytic Achievement in C-C Coupling Reactions.

Complex IrH(PPr) () activates two different σ-bonds of 3-phenoxy-1-phenylisoquinoline, 2-(1-benzimidazol-2-yl)-6-phenylpyridine, 2-(1-indol-2-yl)-6-phenylpyridine, 2-(2-hydroxyphenyl)-6-phenylpyridine, -(2-hydroxyphenyl)-'-phenylimidazolylidene, and 1,3-di(2-pyridyl)-4,6-dimethylbenzene to give IrH{κ--[CH-isoqui-O-CH]}(PPr) (), IrH{κ--[NBzim-py-CH]}(PPr) (), IrH{κ--[Ind-py-CH]}(PPr) (), IrH{κ--[CH-py-CHO]}(PPr) (), IrH{κ--[CH-Im-CHO]}(PPr) (), and IrH{κ--[py-CHMe-CHN]}(PPr) (), respectively. The activations are sequential, with the second generally being the slowest. Accordingly, dihydride intermediates IrH{κ--[CH-isoqui-O-CH]}(PPr) (), IrH{κ--[NBzim-py-CH]}(PPr) (), IrH{κ--[Ind-py-CH]}(PPr) (), and IrH{κ--[py-CHMe-py]}(PPr) () were characterized spectroscopically.

Health Insurance Navigation Tools Intervention: A Pilot Trial Within the Childhood Cancer Survivor Study.

Purpose: Childhood cancer survivors are at increased risk for underinsurance and health insurance-related financial burden. Interventions targeting health insurance literacy (HIL) to improve the ability to understand and use health insurance are needed.

Methods: We codeveloped a four-session health insurance navigation tools (HINT) intervention, delivered synchronously by a patient navigator, and a corresponding booklet.

Loss of WIPI4 in neurodegeneration causes autophagy-independent ferroptosis.

β-Propeller protein-associated neurodegeneration (BPAN) is a rare X-linked dominant disease, one of several conditions that manifest with neurodegeneration and brain iron accumulation. Mutations in the WD repeat domain 45 (WDR45) gene encoding WIPI4 lead to loss of function in BPAN but the cellular mechanisms of how these trigger pathology are unclear. The prevailing view in the literature is that BPAN is simply the consequence of autophagy deficiency given that WIPI4 functions in this degradation pathway.

[Delphi Consensus of Argentine Pulmonologists on the Management of Patients with COPD in Real Life].

Introduction: COPD is the third cause of death globally and in Argentina COPD has a prevalence of 14.5%, but the management of patients in real life is unknown. The objectives of this work were: a) To know the opinions of pulmonologists in Argentina who manage patients with COPD in different aspects of daily practice.

Establishing an Integrative Oncology Service: Essential Aspects of Program Development.

Purpose Of Review: Over the last 2 decades, integrative oncology (IO) has seen exponential growth within cancer care. It aims to combine evidence-based complementary therapies with conventional treatments to improve the well-being and quality of life for individuals dealing with cancer. The proliferation of integrative medicine programs in major cancer centers globally reflects varying approaches shaped by cultural, demographic, and resource-based factors.