Publications by authors named "Ana Lobo de Almeida"
Article Synopsis
- - The study aimed to understand how bleomycin affects human sperm DNA integrity, function, and morphology, which could have implications for male reproductive health.
- - Sperm from 45 healthy participants was exposed to bleomycin in a controlled laboratory setting, revealing significant decreases in sperm vitality and motility, along with increased DNA fragmentation.
- - The findings indicate that bleomycin adversely affects sperm competency, potentially posing risks for male fertility, although the drug did not seem to impact reactive oxygen species levels.
Long-term cancer treatment complications in men include testicular dysfunction and infertility. Although various chemotherapies have been studied, there is limited evidence on their effects, especially for bleomycin. Despite its known lung toxicity, bleomycin's impact on male reproductive health is not well-researched.
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