Efficacy and safety of fractionated conformal radiation therapy in acromegaly: a long-term follow-up study.

Background And Purpose: Conformal, fractionated radiation therapy (XRT) is variably used as a treatment alternative for active acromegaly patients, usually, after failed pituitary surgery. Our objective was to evaluate the long-term efficacy and safety of XRT using strict criteria of biochemical control.

Setting, Design, Patients, And Methods: Retrospective cohort study of 94 patients (73 women, mean age at radiation 53.