Effects of repetitive pinprick stimulation on preterm offspring: Alterations in nociceptive responses and inflammatory hypersensitivity in adulthood.

Introduction: This study investigates the effects of repetitive pinprick stimulation on preterm offspring and its impact on nociceptive responses and inflammatory hypersensitivity in adulthood.

Objectives: The objective is to shed light on the potential long-term consequences of neonatal pain and prematurity on sensory processing.

Methods: Term and preterm rats were subjected to repetitive pinprick (PP) stimulation or control (CC) during the neonatal period.

Nursing Interventions for Patients With Neurogenic Bowel Dysfunction Arising From Complete Spinal Cord Injury: A Scoping Review.

Purpose: We mapped key concepts and identified 4 fundamental nursing interventions for patients with neurogenic bowel dysfunction due to complete spinal cord injury (SCI).

Methods: A scoping review was conducted according to the recommendations of the Joanna Briggs Institute.

Search Strategy: Searches were performed in PubMed, LILACS, CINAHL, COCHRANE, and SCOPUS electronic databases.

Shared decision-making preferences in mental health: does age matter? A systematic review.

Background: Research to date suggests older adults prefer a passive involvement in the clinical decision-making process; however, the empirical evidence underlying this claim in the mental health context is yet to be reviewed systematically.

Aims: To understand whether older adults desire involvement in mental health-related clinical decisions.

Method: A systematic review was conducted to identify primary research that explored mental-health decision-making preferences of people with a mean age of over 55 from January 1990 through to December 2018.

Twelve tips for providing effective student support in undergraduate medical education.

Medical students often require high levels of specialised institutional and personal support to facilitate success. Contributory factors may include personality type, course pressures and financial hardship. Drawing from research literature and the authors' experience, 12 tips are listed under five subheadings: policy and systems; people and resources; students; delivering support; limits of support.

Combined effect of polymeric nanocapsules and chitosan hydrogel on the increase of capsaicinoids adhesion to the skin surface.

This work explored the effect of the encapsulation in polymeric nanocapsules, as well as of the incorporation of such nanoparticles in a chitosan hydrogel, on the skin adhesion and skin penetration/permeation of capsaicinoids (capsaicin and dihydrocapsaicin), which are used as topical analgesic to treat chronic pain. The skin experiments were performed using a modified (drug adhesion and drug diffusion) and a normal Franz diffusion cell (drug diffusion) with porcine skin as membrane. The AUC0-h of the washability profile (% washed away vs.

[Conditions and motivations for the work of nurses and physicians in high complexity emergency services].

This study aimed to evaluate the motivations and conditions offered to the work of nurses and doctors in three high complexity emergency services of the city of Recife, Pernambuco. It is a descriptive transversal type study. It was interviewed 42 nurses and 84 doctors, of a total population of 97 nurses and 469 doctors.

Vitamin K1-loaded lipid-core nanocapsules: physicochemical characterization and in vitro skin permeation.

Background: The incorporation of substances in nanocarriers can modulate and/or manage their delivery profiles (immediate or sustained) and permeation through skin. Consequently, drug nanencapsulation intended for topical treatment can reduce the systemic absorption of the substance.

Objective: To obtain and characterize vitamin K1-loaded lipid core nanocapsules as well as to determine whether the nanoencapsulation influences the skin permeation of this vitamin.

Photostability and skin penetration of different E-resveratrol-loaded supramolecular structures.

It is desirable and challenging to prevent E-resveratrol (E-RSV) from photoisomerizing to its Z-configuration to preserve its biological and pharmacological activities. The aim of this research was to evaluate the photostability of E-RSV-loaded supramolecular structures and the skin penetration profile of chemically and physically stable nanoestructured formulations. Different supramolecular structures were developed to act as carriers for E-RSV, that is, liposomes, polymeric lipid-core nanocapsules and nanospheres and solid lipid nanoparticles.

[Teaching care in nursing graduation according to the perspective of complexity].

This study highlights the teaching of care in Nursing Graduation according to the Complexity Theory, supported by Edgar Morin. This is a qualitative study using Thematic Content Analysis. Twelve individual semi-structured interviews were performed at a private university in the city of São Paulo, Brazil.

Corpus analysis of problem-based learning transcripts: an exploratory study.

Context: Problem-based learning (PBL) is one of the most researched areas of medical education; numerous studies and meta-analyses have examined its overall effectiveness compared with that of traditional methods. Fewer studies have looked at the processes occurring within the PBL group, considering that a key difference between PBL and traditional teaching is the amount of talking in which students engage: a typical PBL week might involve 3-5 hours of talk. Little research has attempted to capture the vocabulary used or to analyse the cognitive processes that occur during PBL discussions and that might contribute to the advantages of this method of learning.

Hospitalizations for HIV/AIDS: differences between sexes.

Background: Women are especially vulnerable to HIV infection because of biological, social, cultural, and economic factors. In Brazil, AIDS was initially seen predominantly in homosexual men, but the epidemic gradually reached a gender balance as increasing numbers of women became infected with HIV.

Objective: The aim of the present study was to identify the clinical and epidemiologic characteristics of hospitalized patients with HIV/AIDS of both sexes and compare the differences between them.

Sudden deafness as a presenting symptom of acoustic neuroma: case report.

Unlabelled: Vestibular schwannoma, also known as acoustic neurinoma, is the most frequent tumor of the cerebellopontine angle, and represents 9% of all intracranial tumors.

Case Report: The authors report a case of sudden deafness with unilateral tinnitus. The patients responded to therapy with Prednisone and Pentoxifylline after the diagnosis of acoustic neurinoma by imaging exams.

[Nursing education in the light of the complexity paradigm].

The objectives of this research were to recognize, interpret and discuss themes that arise out of the speeches of instructors of an undergraduate course of Nursing as guiding sources to a humanized teaching-learning experience in the light of Edgard Morin's Theory of Complexity. It is a qualitative, exploratory and analytic research. The study tried to verify principles of the paradigm of complexity through content analysis, theme modality, in the speeches of 11 instructors, obtained in 2004.

Quality of life and self-esteem after breast asymmetry surgery.

Background: Surgical correction of breast asymmetry involves not only an acceptable aesthetic result but also physical, social, and psychological consequences on the patient's quality of life.

Objective: The authors evaluated the impact of breast asymmetry surgical treatment on self-esteem and health-related quality of life in a group of 35 patients.

Methods: Patients completed the Medical Outcomes Study 36-Item Short Form Health Survey (SF-36), a generic health evaluation tool that covers quality of life across 8 dimensions, and the Rosenberg Self-Esteem Scale, a specific tool for evaluating self-esteem.

[The importance of the Support Network for the stomized patient].

The purpose of the study was to learn about the social support stomized patients turn to, as well as their benefits in facing the changes a new way of life incur in. The methodological reference was oral history of topic lives. Ten half-structured interviews have been conducted with subjects with definitive intestinal ostomy It was used the technique of content analysis, which provided us with three important supporting networks: religious and spiritual beliefs, family and the Ostomy Association.

A possible role of sphingolipids in the aluminium resistance of yeast and maize.

The plasma membrane is most likely the major target for sensing of aluminium (Al), leading to inhibition of plant root-growth. As a result of high external Al, alterations in plasma membrane composition may be expected in order to maintain its properties. As sphingolipids are characteristic components of this membrane, their involvement in membrane adjustment to increased Al concentrations was investigated.

[A paradigmatic glance on nursing care -- a walk to complex care].

The text addresses the Cartesian paradigms (modern) and the complexity paradigm (post-modern of Edgar Morin) aiming to deepen reflection on the theme and understanding to improve nursing. To this end, the authors discuss the model of care of methodical nursing in the Cartesian paradigm defining it as producer of an authoritarian, fragmented and linear care. They point the need to rethink that model because it restricts the autonomy of the people/patient moving in the direction of complex care that provides for customers/actors' participation in their health care planning.