Biological effects and dose-response assessment of diesel exhaust particles on in vitro early embryo development in mice.

An increased risk of early pregnancy loss in women briefly exposed to high levels of ambient particulate matter during the preconceptional period was recently observed. The effects of this exposure on early embryo development are unknown. This study was designed to assess the dose-response and biological effects of diesel exhaust particles (DEP) on in vitro embryo development using the in vitro fertilization (IVF) mouse model.

Effects of chronic exposure to air pollution from Sao Paulo city on coronary of Swiss mice, from birth to adulthood.

To explore the hypothesis that air pollution promotes cardiovascular changes, Swiss mice were continuously exposed, since birth, in two open-top chambers (filtered and nonfiltered for airborne particles View Article and Find Full Text PDF

Effects of São Paulo air pollution on the upper airways of mice.

The nose is the first region of the respiratory tract to come in contact with airborne pollutants. Previous studies have shown that the nasal mucosa can be altered in response to air pollution. In this study, we quantified neutral and acidic mucus in three different levels of the nasal cavity of mice exposed to ambient levels of air pollution in the city of São Paulo, Brazil.