Acute exposure to diesel and sewage biodiesel exhaust causes pulmonary and systemic inflammation in mice.

Biodiesel is a renewable energy source that reduces particle emission, but few studies have assessed its effects. To assess the effects of acute inhalation of two doses (600 and 1200 μg/m) of diesel (DE) and biodiesel (BD) fuels on the inflammatory pulmonary and systemic profile of mice. Animals were exposed for 2 h in an inhalation chamber inside the Container Laboratory for Fuels.

Long-term Air Pollution Exposure, Genome-wide DNA Methylation and Lung Function in the LifeLines Cohort Study.

Background: Long-term air pollution exposure is negatively associated with lung function, yet the mechanisms underlying this association are not fully clear. Differential DNA methylation may explain this association.

Objectives: Our main aim was to study the association between long-term air pollution exposure and DNA methylation.

Effects of ambient levels of air pollution generated by traffic on birth and placental weights in mice.

Objective: To examine whether there is an association between fetal and/or placental weight and exposure to ambient levels of air pollution in mice.

Design: Chronic experiments on mice that were exposed to polluted vs. clean air.

Increased levels of air pollution and a decrease in the human and mouse male-to-female ratio in São Paulo, Brazil.

A significant negative association (R(2) = 0.7642; P=.013) between particulate matter and secondary sex ratio was found when evaluating people in the city of São Paulo, Brazil.