Publications by authors named "Ana Janovic"
Article Synopsis
- This study explores how multicellular cyanobacteria use a protein called FraI, associated with the gene Npun_F4142, to maintain cell communication and coordination for physiological processes like differentiation.
- The FraI knockout mutant shows diminished traits like reduced motility and the inability to form heterocysts, indicating that FraI is vital for the structural integrity of cellular junctions.
- Despite disrupted communication, the mutant still shows some movement in its hormogonia, suggesting that these filaments might move using alternative mechanisms, which enhances our understanding of cell differentiation and the regulatory networks in multicellular cyanobacteria.
Multicellular organisms require controlled intercellular communication for their survival. Strains of the filamentous cyanobacterium Nostoc regulate cell-cell communication between sister cells via a conformational change in septal junctions. These multi-protein cell junctions consist of a septum spanning tube with a membrane-embedded plug at both ends, and a cap covering the plug on the cytoplasmic side.
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