Publications by authors named "Ana J Tadic"
Epidemiology, etiopathogenesis, and management of MRONJ: A European multicenter study.
J Stomatol Oral Maxillofac Surg
September 2024
Article Synopsis
- The study aimed to analyze the characteristics and risk factors of medication-related osteonecrosis of the jaw (MRONJ) across various European Oral and Maxillofacial Surgery centers, to enhance understanding of its epidemiology and treatment trends.
- Data was collected from 537 patients, revealing significant links between metastatic bone disease, advanced MRONJ stages, male gender, and higher recurrence rates of MRONJ.
- Findings suggest that patients with osteoporosis experienced a longer duration of antiresorptive medication before MRONJ onset, while those with metastatic bone cancer, especially prostate cancer or multiple myeloma, had a shorter duration, emphasizing the importance of surgical intervention in managing MRONJ.
Article Synopsis
- The study aimed to assess the risk of postoperative bleeding in patients undergoing dentoalveolar surgery while on direct oral anticoagulants (DOAC) or vitamin K antagonists (VKA), compared to non-anticoagulated subjects.
- Three groups were analyzed: 77 patients on DOAC, 103 on VKA, and 103 controls, with bleeding incidents recorded as 2.9%, 4.8%, and 0.97% respectively, showing no significant differences.
- The findings concluded that neither DOAC nor VKA increased the risk of significant postoperative bleeding, allowing safe surgical procedures without the need to stop anticoagulant therapy.
Background/aim: Patients receiving long-term oral anticoagulant therapy pose a clinical challenge during invasive dental procedures. The goal of this study was to compare different local hemostatic modalities after tooth extraction in patients receiving chronic Vitamin-K antagonist therapy.
Methods: Totally 90 patients with International Normalized Ratio (INR) ≤ 3.