Publications by authors named "Ana Isabel Almeida"

Article Synopsis
  • Growth hormone deficiency can either be congenital (present at birth) or acquired (developing later), with acquired cases often linked to issues in the hypothalamic-pituitary axis.
  • Brain MRI is crucial for diagnosing these deficiencies since it can reveal important structural abnormalities and assess prognosis.
  • The article focuses on how neuroradiologists evaluate pediatric growth hormone deficiency by examining common findings in MRI scans of the pituitary, along with a summary of normal pituitary development and imaging techniques.
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  • This study examines how cardiovascular responses (like heart rate and blood pressure) can help predict the outcomes for children with acute acquired brain injury (ABI) who are admitted to the pediatric intensive care unit (PICU).
  • The research included 72 children, where significant associations were found between conditions like tachycardia and abnormal blood pressure levels and their likelihood of mortality.
  • The findings suggest that the Poincaré SD1/SD2 ratio may be a useful tool for predicting mortality in these patients, indicating the need for larger studies to confirm these results.
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Article Synopsis
  • - The study investigates how preoperative and postoperative audiometric results relate to different radiological staging classifications (Veillon classification and Symons-Fanning classification) in patients undergoing stapes surgery for otosclerosis from 2017 to 2022.
  • - A total of 87 patients were analyzed, revealing that the Symons-Fanning classification showed significant associations with various audiometric thresholds, particularly preoperative bone conduction and postoperative air conduction results, while the Veillon classification was linked predominantly to postoperative air conduction.
  • - The findings suggest that the Symons-Fanning classification is better at predicting both preoperative and postoperative bone conduction outcomes, whereas the Veillon classification excels in predicting postoperative air conduction results; both classifications similarly predicted the occurrence of postoperative air
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Thoracic disc herniation is infrequent and presents a unique set of challenges for both diagnosis and treatment. It is an underdiagnosed entity, mainly due to the non-specific clinical manifestations. Different techniques are used for surgical treatment.

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Adeno-associated viral (AAV) vectors represent one of the leading platforms for gene delivery. Nevertheless, their small packaging capacity restricts their use for diseases requiring large-gene delivery. To overcome this, dual-AAV vector systems that rely on protein trans-splicing were developed, with the split-intein Npu DnaE among the most-used.

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Tension pneumosella has been recognized as a very rare complication of pituitary transsphenoidal surgery. To the best of our knowledge, we report the second case of a pituitary adenoma "pneumo-apoplexy", which is characterized by findings consistent with tension pneumosella in the context of apoplexy of a pituitary adenoma; although it is an extremely rare diagnosis, it should be considered in patients with compatible clinical and radiological findings, particularly with a previous history of transsphenoidal pituitary surgery.

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Posterior mediastinal tumors surgery may be complicated by their proximity to the artery of Adamkiewicz (AKA) and its segmental supplier, increasing the risk of ischemia of the spinal cord. We describe a case of preoperative identification of the AKA with magnetic resonance angiography (MRA) in a 14-month-old boy diagnosed with a thoracic neuroblastoma, thus allowing an accurate surgical planning in order to avoid injury to those vessels. Given the relatively high incidence of posterior mediastinal tumors in the pediatric age, MRA may establish itself as a viable alternative for this purpose, even in young children.

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The pandemic caused by SARS-CoV-2 remains a health care concern, despite vaccination programs. Mucormycosis, especially rhino-orbital-mucormycosis, has been described as a severe complication of COVID-19. Although it has been described mostly in India and other developing countries, few cases in the western world have also been described.

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Cancer aetiology is multifactorial; risk factors comprise obesity, central adiposity, physical inactivity and excessive/ deficient intake of foods and/or nutrients with procarcinogenic/ protective effects. We aim to analyze the pattern of nutritional status, food intake and physical activity in a cohort of cancer patients. This pilot crosssectional study was conducted in 64 outpatients referred for Radiotherapy.

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Nutritional evaluation may predict clinical outcomes, such as hospital length of stay (LOS). We aimed to assess the value of nutritional risk and status methods, and to test standard anthropometry percentiles v. the 50th percentile threshold in predicting LOS, and to determine nutritional status changes during hospitalisation and their relation with LOS.

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Background & Aims: We aimed to test the capacity in identifying patients at nutritional risk, by comparing BMI, recent %weight loss,Nutritional Risk Screening 2002(NRS-2002),Malnutrition Universal Screening Tool(MUST) and Nutritional Risk Index(NRI) with Subjective Global Assessment(SGA),considered the Standard. The main purpose was to select the most consistent screening method for effective integration in daily surgical wards' practice.

Methods: 300 surgical patients were assessed at admission: BMI(categorized by WHO's criteria), weight loss ≥ 5% in previous 6 months, NRS-2002, MUST, NRI, SGA.

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