Publications by authors named "Ana Hernandez Redondo"

Article Synopsis
  • PEth is a specific biomarker for long-term alcohol consumption, accumulating in the body after repeated drinking, making it useful for monitoring drinking behavior.
  • In a study of 142 blood samples with varying blood alcohol concentrations (BAC), PEth levels were analyzed, revealing that specific thresholds could distinguish between moderate and excessive drinking.
  • The findings showed that high concentrations of PEth (≥ 700 ng/mL for 16:0/18:1 and ≥ 300 ng/mL for 16:0/18:2) could indicate prolonged excessive drinking, even when BAC is below the legal driving limit of 1.6‰, suggesting the need for additional assessments of driving ability.
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Background: New psychoactive substances (NPS) have become increasingly prevalent and are sold in internet shops as 'bath salts' or 'research chemicals' and comprehensive bioanalytical methods are needed for their detection.

Methodology: We developed and validated a method using LC and MS/MS to quantify 56 NPS in blood and urine, including amphetamine derivatives, 2C compounds, aminoindanes, cathinones, piperazines, tryptamines, dissociatives and others. Instrumentation included a Synergi Polar-RP column (Phenomenex) and a 3200 QTrap mass spectrometer (AB Sciex).

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The range of novel psychoactive substances (NPS) including phenethylamines, cathinones, piperazines, tryptamines, etc. is continuously growing. Therefore, fast and reliable screening methods for these compounds are essential and needed.

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Background: Ethyl glucuronide (EtG) and ethyl sulfate (EtS) are non-oxidative minor metabolites of ethanol. They are detectable in various body fluids shortly after initial consumption of ethanol and have a longer detection time frame than the parent compound. They are regarded highly sensitive and specific markers of recent alcohol uptake.

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Ethyl glucuronide (EtG) and ethyl sulfate (EtS) are direct alcohol consumption markers widely used nowadays for clinical and forensic applications. They are detectable in blood and urine even after consumption of trace amounts of ethanol and for a longer time frame, being detectable even when no more ethanol is present. The instability of EtG against bacterial degradation in contaminated urine samples and/or the possible postcollection synthesis of this metabolite in samples containing, e.

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Synthetic approaches to 6,6'-disubstituted-2,2'-bipyridine ligands bearing carboxylic acid substituents at the 4,4' or 5,5'-positions are described. Copper(I) complexes with these ligands have been prepared for use in copper-based dye-sensitized solar cells. The single-crystal structures of 6,6'-dimethyl-2,2'-bipyridine-4,4'-dicarboxylic acid (H(2)4), [H(3)6][CF3CO2].

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Dye-sensitized solar cells with carboxylate-derivatized {Cu(I)L(2)} complexes are surprisingly efficient and offer a long-term alternative approach to ruthenium-functionalized systems.

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