Publications by authors named "Ana Guadalupe Gama Cuellar"
Objective: Carcinoma ex-pleomorphic adenoma (CEXPA) represents a malignant transformation from a recurrent or primary pleomorphic adenoma (PA), and the immune response may be essential in this process. Therefore, in this study, we aimed to identify and quantify subpopulations of dendritic cells (DCs) in CEXPA, residual PA in CEXPA (rPA), and PA.
Materials And Methods: A multicenter study was performed collecting salivary gland tumor (SGT) samples from three Oral and Maxillofacial Pathology Centers.
Article Synopsis
- Secretory carcinoma (SC) is a type of salivary gland tumor recognized in the latest World Health Organization classification, resembling breast secretory carcinoma.
- Both types of tumors share a specific fusion gene (ETV6::NTRK3), which can be identified through costly molecular analysis techniques that not all labs can perform.
- The study emphasizes that understanding the typical microscopic features and immunohistochemical profiles of SC is crucial for accurate diagnosis, even without advanced molecular testing.
A solitary fibrous tumor (SFT) is an uncommon mesenchymal tumor characterized by spindle cell proliferation that rarely affects the oral cavity. The clinical and histopathologic features of an oral SFT are described for the benefit of dental practitioners who may encounter one of these rare cases. A 25-year-old man presented with a slow-growing swelling in the left buccal mucosa.
View Article and Find Full Text PDFBackground: Dendritic cells (DCs) are specialized antigen-presenting cells that play a critical role in the immune response against human papillomavirus (HPV) infection, and represent a therapeutic target in cancer.
Objective: To identify and quantify DCs in tonsillar squamous cell carcinoma (TSCC) under the influence of HPV infection.
Methodology: CD1a and CD83 antibodies were used to identify immature dendritic cells and mature dendritic cells by immunohistochemistry in 33 primary TSCC and 10 normal tonsils (NTs), respectively.