Bioprospection of rattlesnake venom peptide fractions with anti-adipose and anti-insulin resistance activity .

Animal venoms are natural products that have served as a source of novel molecules that have inspired novel drugs for several diseases, including for metabolic diseases such as type-2 diabetes and obesity. From venoms, toxins such as exendin-4 () and crotamine () have demonstrated their potential as treatments for obesity. Moreover, other toxins such as Phospholipases A and Disintegrins have shown their potential to modulate insulin secretion in vitro.

Ecological factors shaping ectoparasite communities on heteromyid rodents at Médanos de Samalayuca.

Rodent ectoparasites are vectors for important pathogens of wildlife, domestic animals, and even zoonosis. Nevertheless, distribution patterns of ectoparasites are not fully understood; habitat, season, and host species are important predictors of distribution and prevalence. Heteromyid rodents are considered important reservoirs of diseases, given the presence of different ectoparasites and pathogens in them, and they offer the opportunity to learn about the ecology of parasites.

Population genetic structure of a Chihuahuan Desert endemic mammal, the desert pocket gopher, .

The biogeographic history of the Chihuahuan Desert is complex, driven by numerous physiographic events and climatic changes. This dynamic history would have influenced the flora and fauna of the region including the desert pocket gopher, , a subterranean rodent endemic to the northern Chihuahuan Desert. .

New species of flea of the genus Dactylopsylla Jordan (Insecta: Siphonaptera) from the Flora and Fauna Protection Area Mdanos de Samalayuca, Chihuahua, Mexico.

A new species of Dactylopsylla Jordan, parasites of Geomyidae rodents from Chihuahua, is described and illustrated as D. samalayucae n. sp.

Cytoprotective effects of creosote bush () and Southern live oak () extracts against toxicity induced by venom of the black-tailed rattlesnake ().

The venom of (v) poses a threat to human health, as it contains a mixture of toxins that can cause cytotoxic, necrotic, and hemolytic effects. The present study assessed methanolic and acetone extracts from leaves and flowers of , as well as the bark of as potential suppressors of the toxic effects of v. The content of total phenols, flavonoids, and tannins of the plant extracts were quantified for the suppression of v cytotoxicity in two cell culture models, human lymphocytes and porcine aortic endothelial (PAE) cells.

Toxicological comparison of Crotalus ruber lucasensis venom from different ecoregions of the Baja California Peninsula.

The Baja California Peninsula possesses a mosaic of ecoregions that offers a wide variety of environments for the species that here inhabit. Here we report biological variations in. Crotalus ruber lucasensis venom from arid, semiarid and tropical eco-regions.

Functional Mining of the Spp. Venom Protease Repertoire Reveals Potential for Chronic Wound Therapeutics.

Chronic wounds are a major health problem that cause millions of dollars in expenses every year. Among all the treatments used, active wound treatments such as enzymatic treatments represent a cheaper and specific option with a fast growth category in the market. In particular, bacterial and plant proteases have been employed due to their homology to human proteases, which drive the normal wound healing process.

First report of Siphonaptera parasites in Canis latrans in the Flora and Fauna Protection Area, Médanos de Samalayuca Chihuahua, Mexico.

Siphonaptera are hematophage parasite vectors of both human and animal diseases. We aimed to identify ectoparasites parasitizing a coyote population (Canis latrans) in the northwest region of the Flora and Fauna Protection Area Médanos de Samalayuca, Chihuahua, Mexico. We captured 21 coyotes (15 males and 6 females) during the summer and winter of 2018.

hemotoxic, α-neurotoxic and vasculotoxic effects of the Mexican black-tailed rattlesnake () venom.

The Mexican black-tailed rattlesnake is distributed in the Mexican plateau. Its venom is known to cause hemolysis and presents fibrinogen coagulase, collagenase and fibrinolytic activities. These activities may be associated with hemostatic alterations, such as platelet aggregation, hemolysis and fibrinolysis, often described in ophidic accidents.

Rattlesnake venom induces oxidative stress on human erythrocytes.

Background: Globally, snake envenomation is a well-known cause of death and morbidity. In many cases of snakebite, myonecrosis, dermonecrosis, hemorrhage and neurotoxicity are present. Some of these symptoms may be provoked by the envenomation itself, but others are secondary effects of the produced oxidative stress that enhances the damage produced by the venom toxins.

Capillary damage in the area postrema by venom of the northern black-tailed rattlesnake (Crotalus molossus molossus).

The Northern black-tailed rattlesnake (Crotalus molossus molossus) venom is mainly hemotoxic, hemorrhagic, and neurotoxic. Its effects in the central nervous system are unknown and only poorly described for all Viperidae species in general. This is why we are interested in describe the damage induced by C.