Publications by authors named "Ana Gabriela Krymchantowski"

Article Synopsis
  • Migraine is a common headache disorder that can include visual or sensory disturbances called auras, whereas tension-type headaches (TTH) lack these symptoms.
  • A study investigated 400 patients diagnosed with either migraine or TTH to assess the prevalence of skin ecchymosis (bruising) during and after headache episodes.
  • Results showed that 76% of migraine patients had ecchymosis compared to just 11% of those with TTH, suggesting that the presence of ecchymosis could help differentiate between these two types of headaches.
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Background: Medication overuse headache (MOH) is one of the global health-related problems that imposes significant morbidity. Effective management requires the abrupt cessation of the overused medications, transition therapy in the initial days, and initiation of preventive treatment. The objective of this study is to provide one-year and five-year follow-ups of study participants diagnosed with chronic migraine and MOH.

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Medication-overuse headache (MOH) can develop from primary headaches. MOH is usually the result of overuse of symptomatic medications. It is a noteworthy personal and societal burden.

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Objective: Medication overuse headache (MOH) in chronic migraineurs may be a cause or consequence of the overuse of symptomatic medications for headache attacks. It is highly prevalent in tertiary centers. We compared the efficacy of 3 anti-CGRP monoclonal antibodies with traditional pharmacological agents in patients with chronic migraine (CM) and MOH.

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Background: Children and adolescents may experience pain in the lower limbs, predominantly at the end of the day or during the night, without any relation to organic disease. These pains are often called "growing pains" (GP) by pediatricians and orthopedists. They are commonly attributed to rapid growth.

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Background: Medication-overuse headache is highly prevalent in tertiary care centers. It may be a cause or consequence of the overuse of symptomatic medications for migraine attacks.

Objective: We aimed to compare the efficacy of anti-CGRP monoclonal antibodies (mAbs) added to conventional pharmacological treatments in patients with chronic migraine (CM) and medication overuse headache (MOH).

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Neuropsychiatric disorders associated with coronavirus infections emerged with the coronavirus disease 2019 (COVID-19) pandemic. We describe the clinical, laboratory and radiological features of a patient who presented, after recent COVID-19, two rare neuropsychiatric manifestations: a brief psychotic break followed by severe bilateral peripheral facial palsy.

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Background: Migraine is a highly disabling and prevalent neurological disorder. A peptide, calcitonin gene-related peptide, was identified as involved in migraine pathophysiology and monoclonal anti-CGRP antibodies have been developed.

Aim: To describe the clinical characteristics and therapeutic response of migraine patients treated with monoclonal antibodies.

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Background: COVID-19, a disease caused by SARS-CoV-2, manifests with headache, both in the acute phase and as a post-infection symptom, which may be refractory to usual analgesics.

Objectives: Investigate the therapeutic response of refractory COVID or post-COVID headache to indomethacin.

Methods: This was an observational, retrospective, open and uncontrolled.

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Objetivo: Descrever as características clínicas e as melhores opções terapêuticas para cefaleia em salvas na idade pediátrica. MÉTODO: Com base em pesquisa bibliográfica nas bases de dados médicos PubMed, LiLacs e WoS e usando descritores selecionados, analisamos todos os relatos de casos de cefaleia em salvas em idade pediátrica publicados de 1990 a 2020.

Resultados: Cinquenta e um pacientes (29 meninos e 22 meninas) com idade média (DP) de 9 anos e 7 meses (3 anos e 10 meses), variando de 2 a 16 anos, foram diagnosticados com cefaleia em salvas.

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Article Synopsis
  • The study examines migraine treatment approaches in emergency departments across two regions in Brazil, focusing on medications used and patient outcomes.
  • Found that among 84 migraine patients, the most common medications administered were dipyrone, nonsteroidal anti-inflammatory drugs, and opioids, with an average stay of 8.2 hours.
  • Despite these treatments, less than 30% of patients reported significant headache relief upon discharge, indicating a need for improvements in migraine management practices.
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Article Synopsis
  • - Headaches linked to airplane travel, occurring mainly during takeoff or landing, affect around 14.2% of medical students who fly, with symptoms typically resolving within 30 minutes.
  • - In a study of 155 medical students who took at least 3 flights, 7.5% of flights resulted in headaches, characterized as stabbing pain that often ends with landing.
  • - Despite the discomfort from these headaches, 68.2% of afflicted passengers continued to travel normally on subsequent flights, suggesting that this issue may be more common than previously believed.
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Background And Objective: Sodium divalproate is an effective neuromodulator for migraine prevention. Recommended doses vary from 1,000 to 1,500 mg/day, which may provoke unpleasant side effects as weight gain, tremor, and hair loss. Some patients do respond to lower doses even used once daily in ER presentations, but alternating low daily doses was never studied so far.

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