Publications by authors named "Ana Flavia Moura Mendes"
Front Med (Lausanne)
June 2022
Article Synopsis
- Patients with severe type II leprosy reactions (ENL) often do not respond to traditional treatments like thalidomide and steroids, leading to the exploration of anti-TNF-α therapy as a potential alternative.
- In a study of four such patients in Brazil who underwent rigorous testing to rule out other conditions, three were treated with etanercept and one with adalimumab, resulting in significant improvements without adverse effects from the biologic therapy.
- The therapy not only reduced ENL episodes and allowed for a decrease in immunosuppressant dosages but also led to a notable drop in hospital admissions for ENL complications.
