Deletion of the 1 Gene Increases the Pathogenicity of and Reduces Its Tolerance to the Exogenous Toxic Substances Spermidine and Pyrimethanil.

During the infection of grapevine () by the fungus , the concentration of polyamines, which are toxic substances for the phytopathogen, increases in the grape. Nine NRPS genes have been identified in the genome of , yet the function of five of them remains unknown. For this reason, we have studied the expression of the 9 NRPS genes by RT-qPCR in a medium supplemented with sublethal concentrations of three polyamines (1,3-diaminopropane (1,3-DAP), spermidine (SPD), and spermine (SPM)).