Publications by authors named "Ana Estefania Fernandez-Gomez"
Polypoidal choroidal vasculopathy (PCV) is usually regarded as a subtype of choroidal neovascularization (CNV) that is secondary to age-related macular degeneration (AMD) characterized by choroidal vessel branching, ending in polypoidal lesions. Despite their close association, PCV and neovascular AMD have shown differences, especially regarding patients' treatment response. Currently, antivascular endothelial growth factor (anti-VEGF) drugs, such as ranibizumab, bevacizumab and aflibercept, have demonstrated their efficacy in CNV patients.
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- There is growing interest in incorporating pharmacogenetics into clinical practice, especially for drugs in oncology, psychiatry, and antiviral treatments.
- Despite significant scientific evidence supporting pharmacogenetic tests across various medical fields, various barriers hinder their broader integration.
- The article reviews the current evidence and guidelines for pharmacogenetics related to clopidogrel, warfarin, acenocoumarol, and simvastatin, emphasizing their practical application in everyday healthcare.