Publications by authors named "Ana Esclarin"

Background: Approximately 65%-78% of patients with a spinal cord injury (SCI) develop any symptom of spasticity. The aim of this study was to investigate the tolerability and short-term effects of radial extracorporeal shock wave therapy (rESWT) on plantar flexor spasticity in a patient with incomplete SCI.

Case Summary: An 18-year-old man with an incomplete SCI completed five sessions of rESWT.

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Sensorimotor function of patients with spinal cord injury (SCI) is commonly assessed according to the International Standards for Neurological Classification of Spinal Cord Injury (ISNCSCI). From the ISNCSCI segmental motor and sensory assessments, upper and lower extremity motor scores (UEMS and LEMS), sum scores of pinprick (PP) and light touch (LT) sensation, the neurological level of injury (NLI) and the classification of lesion severity according to the American Spinal Injury Association Impairment Scale (AIS) grade are derived. Changes of these parameters over time are used widely to evaluate neurological recovery.

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Article Synopsis
  • Spinal cord injury (SCI) leads to long-term neurological and systemic issues, including autoimmunity that affects recovery.
  • Researchers found that autoantibodies, which increase one month after SCI, were already present in healthy individuals and target unusual proteins in the spinal cord.
  • The study identified 16 specific self-antigens related to changes following SCI, suggesting that these autoantibodies could explain the development of autoimmunity and pinpoint new areas for future research.
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The aim of this study was to evaluate whether the effect of longer training times (50 instead of 25 min per day) using a robotic device results in a better outcome of walking ability of subjects with a subacute motor complete (American Spinal Injury Association Impairment Scale [AIS]-B) and incomplete (AIS-C) spinal cord injury. Twenty-one patients were enrolled in the study, whereof 18 completed, on average, 34 trainings in 8 weeks. Longer training times resulted in better locomotor function.

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Postoperative wound infection is a severe complication after spinal instrumentation, especially in a patient with spinal injury. We used vacuum-assisted wound closure (VAC) in two patients with spinal cord injury, who presented deep wound infection after spinal instrumentation and were treated with an aggressive irrigation and debridement procedure. Three and four weeks after VAC application, the hardware was completely covered by granulation tissue and a secondary closure was undertaken.

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