Publications by authors named "Ana Escalera"
Article Synopsis
- The study investigates the role of Class II HLA antigens in patients with systemic sclerosis (SSc) from Italy and Spain, focusing on Caucasian ancestry.
- An analysis of 944 SSc patients and 1320 healthy controls reveals strong associations between specific HLA alleles, particularly HLA-DRB1*1104, and the presence of SSc or anti-topo I antibodies.
- The findings contribute to the understanding of the genetic factors associated with SSc in Caucasian populations, highlighting various risk and protective alleles that could inform future research.
Human HAVCR1 gene maps on 5q33.2, a region linked with susceptibility to allergic and autoimmune diseases. The aims of the present study were to define the haplotypes of HAVCR1 gene taking into account both HapMap Project SNP haplotypes and exon 4 variants, to investigate a possible relationship between these haplotypes and mRNA expression levels, and to assess whether HAVCR1 gene is involved in susceptibility to rheumatoid arthritis (RA) and systemic lupus erythematosus (SLE).
View Article and Find Full Text PDFBovine tuberculosis (TB) causes severe economic losses in livestock due to low production, animal deaths and condemnation of carcasses. It is also an important constraint in international trade of animals and animal products. A scientific committee in Great Britain in 1997 concluded that the development of a cattle vaccine would be the best option for long-term control of TB.
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