Molecular Evaluation of the mRNA Expression of the , , , and Genes Linked to Fluconazole Resistance in in a Colombian Population.

Introduction: The study of genes associated with fluconazole resistance, from a molecular perspective, increases the understanding of the phenomenon with a view to its clinical applicability.

Objective: We sought to establish the predictive molecular profile of fluconazole resistance in by analyzing the , , , and genes.

Method: Expression was quantified using RT-qPCR.

First characterization of K. pneumoniae ST11 clinical isolates harboring bla in Latin America.

Antimicrobial resistance due to carbapenemase production in Enterobacteriaceae clinical isolates is a global threat. Klebsiellapneumoniae harboring the bla gene is one of the major concerns in hospital settings in Latin America. The aim of this study was to characterize the antibiotic resistance mechanisms and to typify four carbapenem-resistant K.

[Levels of serum cholinesterase in coffee growers from the Caldas Department, Colombia].

Objective: To determine the levels of serum cholinesterase in coffee growers from the Caldas department and its association with demographic and labor factors.

Methodology: A descriptive study was carried out in a sample of 1 098 farmers from the Upper East and South Center of the Caldas department, through a survey that analyzed characteristics such as sociodemographic, labor, and clinical conditions, as well as cholinesterase levels, determined by Ellman's method.

Results: Regarding the occupational aspect, 90.