Publications by authors named "Ana Dolores Romero Ortiz"

Article Synopsis
  • The study aimed to evaluate how the diagnostic process and time to treatment for idiopathic pulmonary fibrosis (IPF) patients changed from 2011 to 2019, in relation to updates in clinical practice guidelines.
  • A total of 929 out of 1064 patients from a registry were analyzed, revealing that diagnosis methods evolved over time, with a shift from surgical biopsies to non-invasive imaging like chest CT scans.
  • Key findings showed that the average time from symptom onset to diagnosis was 360 days, and many patients experienced delays in receiving antifibrotic treatment, indicating a need for improved diagnostic efficiency.
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Background: Idiopathic pulmonary fibrosis (IPF) is a rare disorder associated with increased mortality and morbidity. There are currently two drugs approved for IPF but their safety and efficacy profile in real-world settings in Spain is not well understood.

Methods: An observational, multicentre, prospective study was carried out among patients with IPF who started treatment with pirfenidone or nintedanib from 2015 to 2021.

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Respiratory function deficits are common sequelae for COVID-19. In this study, we aimed to identify the medical conditions that may influence lung function impairment at 12 months after SARS-CoV2 infection and to analyze the role of alpha-1 antytripsin (AAT) deficiciency (AATD). A cohort study was conducted on hospitalized COVID-19 pneumonia patients in Granada (Spain) during the first infection wave who were referred to a post-COVID-19 hospital clinic.

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Background: Idiopathic pulmonary fibrosis (IPF) is a progressive disease associated with decline in lung function and poor prognosis entailing significant impairment in quality of life and high socioeconomic burden. The aim of this study was to characterize clinical management and resources utilization of patients with IPF in Spain, according to predicted forced vital capacity (FVC) % at baseline.

Methods: Prospective, non-interventional, multicentric real-world data study in patients with IPF in Spain with 12-months follow-up.

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Medical research is progressing to clarify the full spectrum of sub-acute and long-term effects of the post-COVID-19 syndrome. However, most manuscripts published to date only analyze the effects of post-COVID-19 in patients discharged from hospital, which may induce significant bias. Here, we propose a pioneering study to analyze the single and multiple associations between post-COVID-19 characteristics with up to 6-months of follow-up in hospitalized and non-hospitalized COVID-19 patients.

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Background: Changes in lung cancer has been characterized by the increase of cases among women and the increase in adenocarcinomas among other histological subtypes.

Methods: Descriptive analysis of cases diagnosed with lung cancer in Hospital Virgen de las Nieves (Spain) from 1990 to 2010, based on five variables (age, sex, smoking, histology and pathological anatomy). The study establishes associations between these variables and compares the results with the literature.

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