Acute splenic sequestration in a cohort of children with sickle cell anemia.

Objective: To analyze acute splenic sequestration (ASS) in children with sickle cell anemia diagnosed through a newborn screening program in the state of Minas Gerais, Brazil, and followed up at the hematology center in the city of Belo Horizonte, Minas Gerais, Brazil.

Methods: Retrospective cohort of 255 children with sickle cell anemia (Hb SS/Sbeta(0)) born between January 01, 2000, and December 31, 2004, and followed up until December 31, 2006. Data were abstracted from the patients' medical records.