Publications by authors named "Ana Cristina B S Figueiredo"
Cardiac involvement in 2019 coronavirus disease (COVID-19) survivors has been reported frequently. An exacerbated immune response may be the main mechanism of myocardial injury and late cardiac sequelae in this population. We investigated the immune profile in hypertensive and non-hypertensive patients with COVID-19 who developed late cardiac fibrosis and edema, as detected by magnetic resonance imaging (MRI).
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- The study investigated cardiac inflammation in long COVID-19 patients, focusing on those who experienced myocardial injury while hospitalized, using cardiac magnetic resonance (CMR) imaging.* -
- Out of 180 patients, 53 had CMR imaging; results highlighted that significant percentages had myocardial (43.4%) and pericardial (35.8%) late gadolinium enhancement (LGE), indicating heart damage.* -
- Follow-up CMR showed some improvements in heart structure for 17 patients, but overall, many COVID-19 survivors still displayed signs of cardiac remodeling post-recovery.*
Background: Comorbidities such as obesity, hypertension, and diabetes are associated with COVID-19 development and severity, probably due to immune dysregulation; however, the mechanisms underlying these associations are not clear. The immune signatures of hypertensive patients with obesity with COVID-19 may provide new insight into the mechanisms of immune dysregulation and progression to severe disease in these patients.
Methods: Hypertensive patients were selected prospectively from a multicenter registry of adults hospitalized with COVID-19 and stratified according to obesity (BMI ≥ 30 kg/m²).
Purpose: Myocardial injury is common in hypertensive patients with 2019 coronavirus disease (COVID-19). Immune dysregulation could be associated to cardiac injury in these patients, but the underlying mechanism has not been fully elucidated.
Methods: All patients were selected prospectively from a multicenter registry of adults hospitalized with confirmed COVID-19.
Myocardial injury (MI), defined by troponin elevation, has been associated with increased mortality and adverse outcomes in patients with coronavirus disease 2019 (COVID-19), but the role of this biomarker as a risk predictor remains unclear. Data from adult patients hospitalized with COVID-19 were recorded prospectively. A multiple logistic regression model was used to quantify associations of all variables with in-hospital mortality, including the calculation of odds ratios (ORs) and confidence intervals (CI).
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