Publications by authors named "Ana Cristina A Silva"
Gas chromatography coupled to mass spectrometry (GC-MS) characterization and evaluation of antibacterial bioactivities of the essential oils from Aubl., L. e Kunth.
Z Naturforsch C J Biosci
January 2021
Article Synopsis
- * Key chemical components identified through gas chromatography included β-copaen-4-α-ol, spathulenol, and germacrene B, which were largely present in the essential oils.
- * While the oils showed limited activity against standard and multidrug-resistant bacteria, they significantly inhibited some strains of multidrug-resistant bacteria and enhanced the effectiveness of antibiotics like norfloxacin and gentamicin, indicating potential for synergistic effects.
Considering the evidence that essential oils, as well as safrole, could modulate bacterial growth in different resistant strains, this study aims to characterize the phytochemical profile and evaluate the antibacterial and antibiotic-modulating properties of the essential oil (EOOO) and safrole against efflux pump (EP)-carrying strains. The EOOO was extracted by hydrodistillation, and the phytochemical analysis was performed by gas chromatography coupled to mass spectrometry (GC-MS). The antibacterial and antibiotic-modulating activities of the EOOO and safrole against resistant strains of and were analyzed through the broth microdilution method.
View Article and Find Full Text PDFThis report describes two patients who presented acute disseminated and severe toxoplasmosis as the first opportunistic disease related to acquired immunodeficiency syndrome. At admission, clinical and laboratory findings were similar to sepsis or septic shock and a fast evolutive course to death occurred in both cases. At necropsy, an inflammatory reaction and presence of a great number of Toxoplasma gondii cysts and tachyzoites were observed in most organs examined.
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