Safety evaluation of the food enzyme containing endo-polygalacturonase and β-glucosidase from the non-genetically modified strain ARO.

The food enzyme containing endo-polygalacturonase and β-glucosidase (EC 3.2.1.

Safety evaluation of the food enzyme endo-1,4-β-xylanase from the non-genetically modified strain HBI-TX01.

The food enzyme endo-1,4-β-xylanase (4-β-d-xylan xylanohydrolase; EC 3.2.1.

Safety evaluation of the food enzyme triacylglycerol lipase from the non-genetically modified strain AE-LAYH (B).

The food enzyme, a triacylglycerol lipase (triacylglycerol acylhydrolase; EC 3.1.1.

Safety evaluation of the food enzyme endonuclease from the non-genetically modified strain NP 11-15.

The food enzyme endonuclease ( nuclease S; EC 3.1.30.

Safety evaluation of an extension of use of the food enzyme pullulanase from the non-genetically modified strain AE-PL.

The food enzyme pullulanase (pullulan 6-α-glucanohydrolase; EC 3.2.1.

Safety evaluation of the food enzyme inulinase from the non-genetically modified strain NZYM-KF.

The food enzyme inulinase (1--d-fructan fructanohydrolase; EC 3.2.1.

Safety evaluation of a food enzyme with phospholipase A and lysophospholipase activities from the genetically modified strain PLN.

The food enzyme with phospholipase A (phosphatidycholine 1-acylhydrolase, EC 3.1.1.

Safety evaluation of the food enzyme glutaminase from the genetically modified strain NZYM-JQ.

The food enzyme glutaminase (l-glutamine amidohydrolase EC 3.5.1.

Safety evaluation of the food enzyme phosphodiesterase I from the non-genetically modified strain FDA.

The food enzyme phosphodiesterase I (oligonucleotide 5'-nucleotidohydrolase; EC 3.1.4.

Safety evaluation of the food enzyme preparation D-psicose 3-epimerase from the non-genetically modified strain SYG27B.

This assessment addresses a food enzyme preparation consisting of the immobilised non-viable cells of the non-genetically modified bacterium identified by the applicant (Samyang Corporation) as strain SYG27B. This strain produces the enzyme D-psicose 3-epimerase (EC 5.1.

Safety evaluation of the food enzyme mucorpepsin from the non-genetically modified strain FRO.

The food enzyme mucorpepsin (EC 3.4.23.

Safety evaluation of the food enzyme β-galactosidase from the non-genetically modified strain AE-BLC.

The food enzyme β-galactosidase (β-d-galactoside galactohydrolase; EC 3.2.1.

Safety evaluation of the food enzyme endo-1,4-β-xylanase from the non-genetically modified strain 278.

The food enzyme endo-1,4--xylanase (4--d-xylan xylanohydrolase; EC 3.2.1.

Safety evaluation of the food enzyme α-l-rhamnosidase from the non-genetically modified strain AE-HP.

The food enzyme α-l-rhamnosidase (-l-rhamnoside rhamnohydrolase; EC 3.2.1.

Safety evaluation of the food enzyme catalase from the non-genetically modified strain AE-CN.

The food enzyme catalase (hydrogen-peroxide:hydrogen-peroxide oxidoreductase; EC 1.11.1.

Safety evaluation of a food enzyme containing endo-polygalacturonase and pectin lyase activities from the non-genetically modified strain NZYM-PE.

The food enzyme with the declared activities endo-polygalacturonase ((1-4)-α-D-galacturonan glycanohydrolase; EC 3.2.1.

Safety evaluation of the food enzyme α-amylase from the non-genetically modified strain AS 29-286.

The food enzyme α-amylase (4-α-d-glucan glucanohydrolase; EC 3.2.1.

Safety evaluation of the food enzyme glucan 1,4--glucosidase from the non-genetically modified strain NZYM-BO.

The food enzyme glucan 1,4--glucosidase (4--d-glucan -glucohydrolase; EC 3.2.1.

Increasing Energy Density with Capacity Preservation by Aluminum Substitution in Sodium Vanadium Phosphate.

Highly Al-substituted C-coated NaVAl(PO) compounds with a sodium superionic conductor structure are synthesized by a single and easily scalable sol-gel route. The effect of the experimental conditions is examined. Their structural, chemical, and morphological features are described.

Classification and reporting of severity experienced by animals used in scientific procedures: FELASA/ECLAM/ESLAV Working Group report.

Directive 2010/63/EU introduced requirements for the classification of the severity of procedures to be applied during the project authorisation process to use animals in scientific procedures and also to report actual severity experienced by each animal used in such procedures. These requirements offer opportunities during the design, conduct and reporting of procedures to consider the adverse effects of procedures and how these can be reduced to minimize the welfare consequences for the animals. Better recording and reporting of adverse effects should also help in highlighting priorities for refinement of future similar procedures and benchmarking good practice.

Neuroanatomy-based matrix-guided trimming protocol for the rat brain.

Brain trimming through defined neuroanatomical landmarks is recommended to obtain consistent sections in rat toxicity studies. In this article, we describe a matrix-guided trimming protocol that uses channels to reproduce coronal levels of anatomical landmarks. Both setup phase and validation study were performed on Han Wistar male rats (Crl:WI(Han)), 10-week-old, with bodyweight of 298 ± 29 (SD) g, using a matrix (ASI-Instruments(®), Houston, TX) fitted for brains of rats with 200 to 400 g bodyweight.

Circadian profile of peripheral hormone levels in Sprague-Dawley rats and in common marmosets (Callithrix jacchus).

Aim: in the present study, we report the circadian profiles of a wide panel of hormones measured in rats and common marmosets (Callithrix jacchus), under physiological conditions, paying special attention to minimising the stress imposed on the animals.

Materials And Methods: blood collections were performed over a 24-hour period for the analysis of stress and pituitary hormones, metabolic markers and cytokines from male cannulated rats connected to a fully automatic system, and healthy marmosets in which gender differences were also evaluated.

Results: in rats, a significant time effect was observed for corticosterone, prolactin (PRL), thyroid stimulating hormone (TSH), growth hormone, follicle-stimulating hormone, brain-derived neurotrophic factor, total ghrelin, insulin, leptin, insulin-like growth factor-1, adiponectin and interleukin-10.

Reduction of isoflurane MAC by fentanyl or remifentanil in rats.

Objective: The main objective of the study was to determine the effects of three different infusion rates of fentanyl and remifentanil on the minimum alveolar concentration (MAC) of isoflurane in the rat. A secondary objective was to assess the cardiovascular and respiratory effects of the two opioid drugs.

Animal Population: Thirty-seven male Wistar rats were randomly allocated to one of six treatment groups.

Use of cyanoacrylate gel as a substitute for dental cement in intracerebroventricular cannulations in rats.

This study was carried out to determine whether cyanoacrylate gel was suitable for use as a substitute for dental cement during brain implant surgery of rats. Intracerebroventricular (ICV) cannulations were performed in 24 rats by two surgeons, one with 3 years' experience in this type of surgery, and one novice, with only basic training performed on cadavers. Each surgeon prepared six randomly allocated animals using dental cement to secure the cannula and six with cyanoacrylate gel.