Human Aquaporin-5 Facilitates Hydrogen Peroxide Permeation Affecting Adaption to Oxidative Stress and Cancer Cell Migration.

Reactive oxygen species (ROS), including HO, contribute to oxidative stress and may cause cancer initiation and progression. However, at low concentrations, HO can regulate signaling pathways modulating cell growth, differentiation, and migration. A few mammalian aquaporins (AQPs) facilitate HO diffusion across membranes and participate in tumorigenesis.

Spatial Distribution of Metals and Associated Risks in Surface Sediments Along a Typical Urban River Gradient in the Beijing Region.

Surface sediments from Beiyun River located in the rapidly urbanized Beijing metropolis were collected and analyzed for heavy metals (As, Cd, Cr, Cu, Mn, Ni, Pb, and Zn) to investigate their spatial distribution pattern, ecotoxicology and source identification. Results indicated the average heavy metal concentrations of Cd, Cr, Cu, Pb, and Zn were approximately 4, 2, 3, 2, and 4 times higher than their background values. Spatially, we found the concentrations of heavy metals made significant change in four sections along urbanized river gradients.