Standardization of organoid culture for evaluation of melanogenesis induced by UVB, UVA and visible light.

Background: Organoid cultures are primary cultures that maintain architectural characteristics and the relationships between cells, as well as the extracellular matrix. They are alternatives for pathophysiological or therapeutic investigation rather than animal and in vitro tests.

Objective: Development of a cutaneous organoid culture model, aiming at the study of radiation-induced melanogenesis.