Clinical predictors of abnormal esophageal pH monitoring in preterm infants.

Background: Risk factors for gastroesophageal reflux disease in preterm neonates have not been yet clearly defined.

Aim: To identify factors associated with increased esophageal acid exposition in preterm infants during the stay in the neonatal unit.

Methods: A case-control study in preterm infants who had undergone prolonged monitoring of distal esophageal pH, following clinical indication.