Mosquito-disseminated pyriproxyfen for mosquito-borne disease control in Belo Horizonte, Brazil: a pragmatic, before-after control-intervention paired-series trial.

Background: Mosquitoes transmit important human pathogens, including dengue virus, but are notoriously hard to control. Mosquito-disseminated pyriproxyfen (MDPPF) uses the mosquitoes themselves to transfer particles of pyriproxyfen, a potent larvicide and pupicide, from lure dissemination stations to untreated larval habitats. MDPPF can reduce mosquito densities, but possible epidemiological effects remain to be measured.

Characterization of dengue cases confirmed using the database linkage technique: assessment of virus circulation in Belo Horizonte, Brazil, 2009-2014.

Objective: to describe dengue virus circulation in Belo Horizonte, Brazil, from 2009 to 2014.

Methods: this is a series study of cases of dengue infected by different virus serotypes, identified by virus isolation or RT-PCR; database linkage was performed between the Notifiable Health Conditions Information System (SINAN), the Brazilian National Health System Hospital Information System (SIH/SUS) and the Laboratory Environment Manager (GAL).

Results: 91.