Publications by authors named "Ana C Soares"

The liver is the most common organ injury associated with blunt trauma. Blunt hepatic trauma, due to the high kinetic impact on the liver, causes compression and parenchymal disruption, leading to tears in its vascular structures. By contrast, gallbladder injury is rare because it is located beneath and shielded by the liver.

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Background Breast-conserving surgery (BCS) is standard for early breast cancer, yet achieving clear surgical margins remains challenging. Ultrasound (US)-guided BCS has emerged as a potential alternative to wire-guided surgery, but its efficacy compared to traditional methods requires evaluation. Methods A retrospective review of patients undergoing BCS from April 2022 to April 2023 at the Portuguese Institute of Oncology of Porto (IPO-Porto) was conducted.

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Bovine leptospirosis is a major reproductive disease. As cows can be leptospiral carriers both on the renal and genital tract, diagnosis can be challenging, with an underlying risk of misdiagnosis. Traditionally, the infection has been diagnosed by culturing or PCR from urine samples.

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Chylous ascites is the exudation from lymphatic content to the peritoneum and is a rare situation that mostly occurs following medical causes like neoplasms or cirrhosis. However, trauma to the lymphatic system due to compression by masses or altered anatomy can be a trigger too. We describe a rare combination of a primary small bowel volvulus in a young healthy adult causing chylous ascites.

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This study evaluated the effect of fluoxetine (FLU) on planktonic and biofilm growth and the antimicrobial susceptibility of . The minimum inhibitory concentrations (MICs) for FLU were determined by broth microdilution. Its effect on growing and mature biofilms and its interaction with antibacterial drugs were evaluated by assessing biofilm metabolic activity, biomass and structure through confocal microscopy.

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Article Synopsis
  • Sponges have co-evolved with microbes for over 400 million years, classified into Low Microbial Abundance (LMA) and High Microbial Abundance (HMA) based on their microbial content.
  • This study investigates sponges from the Great Amazon Reef System (GARS), revealing that LMA sponges derive nutrition from the Amazon River Plume, while HMA sponges maintain specialized symbiotic microbes.
  • Findings indicate distinct microbial communities in LMA and HMA sponges, with LMA sponges showing higher phage abundance and HMA sponges exhibiting mechanisms for phage defense, highlighting their ecological roles and interactions in nutrient cycling.
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Objectives: to build and validate educational self-care technology for informal caregivers.

Methods: methodological study, anchored in the Delphi technique, carried out in a municipality in the state of Paraná, Brazil, between September 2018 and November 2019. It was developed in three stages: situational diagnosis; elaboration of educational technology; content and appearance validation by expert judges and informal caregivers, using the content validity index and coefficient of variation.

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  • The Great Amazon Reef System (GARS) is a significant marine ecosystem located near the Amazon River, with rhodolith holobionts being key components in the area, which spans 56,000 km.
  • Research aims to determine if environmental conditions like light, temperature, and depth affect the microbiomes of rhodoliths across different sectors (northern, central, southern) of GARS.
  • Findings show that the microbiomes of rhodoliths are mostly similar across the study area but exhibit subtle differences, especially in the southern sector, where higher light leads to increased abundance of certain microbial groups and functional categories linked to photosynthesis and iron metabolism.
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Biological rhythms are a ubiquitous feature of life. Most bodily functions, including physiological, biochemical, and behavioral processes, are coupled by the circadian rhythm. In the cardiovascular system, circadian fluctuations regulate several functions, namely heart rate, blood pressure, cardiac contractility, and metabolism.

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  • The study investigates the aftermath of the Fundão tailings dam failure on the water quality of the Doce River by analyzing metagenomics and physicochemical data shortly after the disaster and again at 6 and 10 months later.
  • Immediately following the dam failure, water quality deteriorated significantly, with extremely high levels of suspended particulate matter, turbidity, and dissolved metals, while dissolved oxygen fell below legal standards in some areas.
  • Six months post-disaster, water quality improved, aligning with Brazilian guidelines, but notable changes occurred in microbial communities, showing increased diversity and alterations in metabolic functions related to iron and nitrogen cycling.
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Effective vocabulary interventions for children with hearing loss, including children who are bilingual, are needed because of persistent vocabulary deficits in this population. Current instructional practices for children with hearing loss who are bilingual vary in the degree to which they incorporate the language the child uses at home. Unfortunately, there is little direct evidence as to whether bilingual or monolingual instructional practices yield greater benefits for these children.

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  • * A three-year study in Ishigaki Island showed high nutrient levels and microbial abundance, with concern over correlations between high turf cover, low coral cover, and low fish biomass.
  • * The research suggests that multiple stressors like eutrophication, overfishing, and climate change are synergistically harming coral reefs in high-energy environments, potentially leading to their collapse.
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Objective: To evaluate both the performance and acceptability of a method coupling self-sampling with detection of cervical malignancy via elevated HPV 16 and 18 E6 oncoproteins (OncoE6™ Cervical Test) in remote areas in Brazil.

Methods: Women living in rural villages in proximity to Coari city, Amazonas, Brazil were invited to participate in a cervical cancer screening study. 412 subjects were enrolled; there were no refusals.

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  • - Marine sponges host complex microbial communities that may be responsible for producing secondary metabolites, like bromopyrrole alkaloids, which have notable biological activities.
  • - Research on sponge species Agelas spp. and Tedania brasiliensis revealed distinct microbial halogenases, indicating a species-specific presence and a correlation between halogenase encoding bacteria abundance and bromopyrrole production.
  • - The study suggests that sponges with numerous CRISPR sequences, like Agelas spp., may protect themselves from phage infections, while phages can facilitate the horizontal transfer of halogenases among holobionts, especially in more adaptable hosts like Tedania spp.
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  • The study focuses on the diversity and structure of virus assemblages in the Amazon River-ocean continuum, highlighting their importance in global carbon and nutrient cycling.
  • Researchers collected viral DNA sequences from 12 locations along the river and plume, yielding 29,358 scaffolds and 15 new complete viral genomes, revealing distinct virome characteristics between the river and plume ecosystems.
  • Findings indicate that bacteriophages were widespread, while eukaryotic viruses were more prevalent in the river; the study emphasizes the influence of water physical and chemical parameters, especially salinity, on viral distribution and contributes to understanding the role of viruses in the organic matter cycle.
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Kaurenoic acid derivatives were prepared and submitted to in vitro assays with the fungus Colletotrichum lindemuthianum, which causes anthracnose disease in the common bean. The most active substances were found to be methyl and p-bromobenzylesters, 7 and 9, respectively, of the hydrogenated kaurenoic acid, which presented a minimum inhibitory concentration (MIC) of 0.097 and 0.

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  • Large rivers, like the Amazon, significantly disrupt reef distributions on tropical shelves by affecting salinity, pH, light penetration, and sedimentation over a large area of the North Atlantic.
  • Despite these harsh conditions, a complex carbonate system thrives off the Amazon's mouth, characterized by unique hard-bottom structures, originating from sedimentation during low sea levels and continuing in certain areas.
  • These carbonate structures support diverse marine life, including sponges and filter feeders, and act as a connectivity corridor for reef-associated species, offering insights into how tropical reefs can adapt to challenging conditions, which are becoming more common globally.
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  • Dengue fever poses a significant public health threat in Brazil, leading to serious outbreaks and health complications.
  • This study examines maternal and fetal deaths linked to dengue, analyzing tissues from the placenta and umbilical cord using advanced molecular techniques.
  • The presence of dengue virus markers in these tissues suggests that they could serve as valuable tools in investigating fatal cases of dengue, particularly those affecting mothers and their unborn children.
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  • - The study focuses on the transition between cold, nutrient-rich waters and warm, nutrient-poor waters in upwelling regions, examining the microbial and viral communities involved during this change.
  • - By analyzing taxonomic, metabolic compositions, and physical-chemical data, researchers identified various metabolic processes and ecological interactions among planktonic microbes in both downwelling and upwelling states.
  • - Key findings revealed that microbial activities such as nitrogen recycling and photosynthesis play significant roles in downwelling, while specific groups like diatoms and certain bacteria dominate upwelling, indicating their importance in the overall functioning of these ecosystems.
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This cross-sectional study evaluates the relations between the water load test in childhood functional gastrointestinal disorders with food intake and nutritional status. Patients with functional dyspepsia required a lower maximum water intake to produce fullness (n = 11, median = 380 mL) than patients with irritable bowel syndrome (n = 10, median = 695 mL) or functional abdominal pain (n = 10, median = 670 mL) (P < 0.05).

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Plant species naturally selected by sheep grazing in the Cerrado region of Brazil were assessed in vitro for activity against Haemonchus contortus. One year of observations showed the plant families in the region exhibiting greatest richness to be Fabaceae, Rubiaceae, Malpighiaceae, Bignoniaceae, Myrtaceae, and Annonaceae. Nine species commonly selected by grazing sheep showed variation in the selectivity index with respect to the dry and rainy seasons.

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Brevipalpus phoenicis (Geijskes) is a cosmopolitan and polyphagous mite that transmits important phytoviruses, such as coffee ringspot virus, passion fruit green spot virus and Citrus leprosis virus C. To characterise the dynamics of the probability and the rate of B. phoenicis infestation in response to edaphic and climatic factors, monthly inspections were performed in nine orchards in a citrus region of the State of Bahia, Brazil, for 35 months.

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Article Synopsis
  • Sponges host complex communities of microbes, and while their taxonomic makeup is known, understanding their functional roles in symbiosis is a key challenge.
  • Researchers analyzed the microbiota of two sponge species, Didiscus oxeata and Scopalina ruetzleri, from the St Peter and St Paul archipelago using metagenomics.
  • Findings revealed that while both sponge communities share core functions, they differ in microbial composition, diversity, and metabolic strategies, particularly in how they process carbon, nitrogen, and sulfur.
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Objective:: To assess the knowledge and practice of pediatricians about infants with physiological reflux and gastroesophageal reflux disease.

Methods:: 140 pediatricians were interviewed during two scientific events in 2009 and 2010. The questions referred to two clinical cases of infants.

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Objective: To determine the geographical distribution of hemoglobinopathies in the State of Pernambuco, to characterize the children with these diseases and to describe factors associated with their follow-up at the referral center during the period from 2003 to 2010.

Methods: A retrospective, cross-sectional, descriptive study was carried out of 275 medical records from a total of 302 children with hemoglobinopathies diagnosed by the National Neonatal Screening Program in the State of Pernambuco in the study period. Microsoft Excel was used for data processing and analysis.

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