Publications by authors named "Ana C Romani"
Guinea pigs have historically been used as a food source and are also an important model for studying the human intestines. Fasting is the act of temporarily stopping the intake of food. This process can alter the microbiota of various animals.
View Article and Find Full Text PDFThis study investigated the effect of host genetics on the structure and composition of the cecum microbiota of three breeds of guinea pigs: Andina, Inti, and Peru. Fifteen guinea pigs were distributed into three groups according to their breed: Andina (5), Inti (5), and Peru (5). We discovered that four main phyla were shared between the three breeds: Bacteroidota, Firmicutes, Spirochaetota, and Synergistota.
View Article and Find Full Text PDFArticle Synopsis
- A dangerous bacterium, associated with multiple diseases and known for its lethal toxins, currently lacks a safe and effective vaccine for humans.
- Researchers computationally screened the bacterium's entire proteome to identify immunogenic proteins and potential vaccine candidates, focusing on proteins like Collagenase A and Exo-alpha-sialidase.
- The study also highlighted promising multi-epitope proteins designed for future vaccine development, which could be evaluated in preclinical trials for their ability to stimulate immune responses and protect against infections.