Publications by authors named "Ana C R Lacerda"

The Modified Sphygmomanometer Test (MST) is a method for assessing muscle strength that offers objective measures similar to those of a portable dynamometer, while also being cost-effective. However, previous studies have not investigated the measurement properties of the MST in adolescents. Thus, the objectives of the study were (1) to examine the concurrent criterion validity, test-retest and interrater reliability of the Modified Sphygmomanometer Test (TMS) for assessing muscle strength in adolescents, (2) to calculate the Standard Error of Measurement (EPM) and the smallest real difference (SRD) of muscle strength values; and (3) analyze the different forms of operationalization and their influence on the results obtained.

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Purpose: To verify the accuracy of respiratory muscle strength in identifying systolic dysfunction in patients with Chagas cardiomyopathy (ChC), and to validate optimal cutoff points based on respiratory muscle strength.

Methods: First, 72 patients with ChC were enrolled and underwent echocardiography and assessment of respiratory muscle strength by manovacuometry. Inspiratory and expiratory muscle strength was defined by maximal inspiratory pressure (MIP) and maximal expiratory pressure (MEP), respectively.

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Article Synopsis
  • Aging can lead to sarcopenic obesity, a condition where individuals are obese while also experiencing muscle loss and decreased strength due to sarcopenia.
  • The study evaluated 156 older women to analyze the effects of obesity, sarcopenia, and sarcopenic obesity on body composition, functional performance, and muscle strength; results showed that 32.7% had obesity, 15.4% had sarcopenia, and 25% were classified as having sarcopenic obesity.
  • Findings revealed that women with sarcopenic obesity had worse physical performance and lower muscle-specific strength compared to those without, highlighting the need to consider muscle strength in diagnosing and addressing sarcopenic obesity in
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Background: Sarcopenic obesity (SO) is a clinical disorder characterized by increased adiposity and decreased muscle mass and function, commonly observed in older adults. However, most of the studies that investigated SO prevalence rates were not based on current standardized diagnostic methods. Thus, this study aims to estimate the prevalence rates of SO and their level of agreement using different instruments proposed by the European Society for Clinical Nutrition and Metabolism (ESPEN) and the European Association for the Study of Obesity (EASO) Consensus, in a sample of hospitalized older adults with severe obesity.

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Objective: To assess the association of residual diuresis with sarcopenia in patients with Chronic Kidney Disease (CKD) on hemodialysis.

Methods: Through a cross-sectional study, patients on hemodialysis were subjected to a Dual Energy Radiologic Absorption (DEXA) exam to record muscle mass. Based on the volume of urine collected in 24 hours, patients were classified as anuric (diuresis ≤ 100 mL/day) or non-anuric (diuresis > 100 mL/day).

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Background: Flexibility is a component of functional capacity and is relevant in maintaining the musculature and structures adjacent to the joints. Then, the improvement of the flexibility must be a critical goal in the rehabilitation programs. By improving flexibility in knee osteoarthritis (KOA) individuals, the pain is relieved, the risk of injury is reduced, and the need for surgical interventions is delayed.

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Introduction: Chronic venous disease (CVD) is a highly prevalent disease that presents a wide spectrum of clinical expressions due to abnormalities in the venous system. Patients often have major functional changes that can limit daily activities. However, the functional factors associated with the severity of the disease remain poorly understood.

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Chagas cardiomyopathy (ChC) presents many biopsychosocial complexities, highlighting the need to have patient self-report questions. This study demonstrates the scope of the use of patient-reported outcome measures (PROMs) in patients with ChC and highlights the main research gaps. This is a scoping review and the search strategy was performed in the Online Medical Literature Analysis and Retrieval System (MEDLINE), Excerpta Medica database (EMBASE), Accumulated Index of Nursing and Allied Health Literature (CINAHL), Cochrane Central, Latin American Literature and Caribbean in Health Sciences (LILACS) and Diagnostic Test Accuracy (DITA).

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Article Synopsis
  • The study aims to explore the relationship between inflammatory biomarkers, physical function, and cognitive decline in older women, focusing on early diagnosis strategies.
  • Using various tests, including the Mini Mental State Examination and physical performance assessments, it analyzed cognitive function in 71 participants.
  • Key findings suggest that poorer physical function and elevated leptin levels are linked to decreased cognitive function, providing insights into the underlying causes of cognitive decline and potential strategies for intervention.
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Despite current literature pointing to a link between shortened telomeres and aging, chronic diseases, and geriatric syndromes, the precise implications of this connection remain unclear. The aim of this exploratory, cross-sectional, observational study was to investigate the association between the relative telomere length (RTL) of peripheral blood leukocyte subtypes (mononuclear cells and granulocytes) and physical performance using the Short Physical Performance Battery (SPPB) in older adults. A cohort of 95 participants was recruited, which included men and women aged over 60 years (70.

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Aims: To investigate the frequency and the factors associated with urinary incontinence (UI) in a sample of middle-aged and older women with lower limb osteoarthritis (OA).

Methods: Women aged 50 years or older with clinical hip/knee OA diagnoses were recruited for this cross-sectional study. Self-reported UI and type, sociodemographic characteristics, medical conditions, physical activity level, anthropometric and body composition measurements, muscle strength, and physical function were assessed.

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Knowledge of how the different types of sedentary behaviors (SB) are associated with functional limitations can guide professionals who work with older adults on better recommendations about the amount of daily time that should be encouraged in each type of SB. The objective was to estimate the associations between two SB typologies (SB television [TV] and SB computer/internet) and the presence of handgrip strength, lower limb strength, gait speed, and balance limitations in Brazilian community-dwelling older adults. This is a cross-sectional study with 1,298 community-dwelling older adults (≥60 years).

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Background: In the last decade a large number of studies proposed and/or validated equations to estimate the Resting Energy Expenditure (REE) in adults and/or older adults, however, no equation currently available showed good accuracy for older adults with severe obesity. Thus, this study aimed to develop and validate new predictive equations for REE, based on data from the indirect calorimetry, in Italian older adults with severe obesity.

Methods: A retrospective study was as conducted with 764 Caucasian older adults with severe obesity (age range: 60-74 years and BMI ≥ 35 kg/m/²).

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Background: Although it is well known that obesity is frequently associated with reduced levels of habitual physical activity (HPA), which contributes to determining severe oxidative stress and inflammatory state, this association is however unknown in preschoolers so far. This study aimed to investigate the association between biomarkers of redox status and cytokines with different patterns of HPA according to the adiposity of preschoolers.

Methods: A cross-sectional study was conducted in 50 preschoolers (25 overweight/obese, OW/OB and 25 eutrophic, EU), matched for age, sex, economic level, and maternal education.

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Objective: Chagas cardiomyopathy (ChC) is the most severe clinical form of Chagas disease and, in association with psychosocial factors, can compromise the health-related quality of life (HRQoL) of affected patients. To date, there is no specific instrument to assess the HRQoL of these patients, and the Minnesota Living with Heart Failure Questionnaire (MLwHFQ), specific for heart failure, is being used both in research and current clinical practice. Therefore, we aimed to verify the validity of the MLwHFQ in the assessment of HRQoL of patients with ChC.

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Background: Functional impairment can be detected from the onset of heart disease in patients with Chagas cardiomyopathy (ChC) and the prognostic value of the end-tidal carbon dioxide at peak exercise (PETCO peak) should be investigated.

Objective: To verify the prognostic value of PETCO peak in patients with ChC.

Methods: Seventy-six patients with ChC (49.

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Article Synopsis
  • - Recent studies indicate that Sarcopenia, a condition characterized by loss of muscle mass and strength, affects inflammatory biomarkers, but the understanding of how these biomarkers change at different stages of the condition is limited.
  • - This study involved 71 older Brazilian women, assessing muscle strength, physical performance, and body composition, and classified Sarcopenia based on the EWGSOP2 criteria.
  • - Results showed that as Sarcopenia progressed, levels of specific inflammatory biomarkers (BDNF, IL-8, sTNFr-1, and sTNFr-2) increased, suggesting these could help in diagnosing and determining the severity of Sarcopenia in older women.
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Article Synopsis
  • The study investigated the prevalence of sarcopenia among older Brazilian women using diagnostic tools recommended by the European Working Group on Sarcopenia in Older People 2 (EWGSOP2).
  • It found significant differences in sarcopenia prevalence rates based on various assessment methods, with some tools indicating rates as high as 40.6% while others showed much lower figures.
  • The results highlighted a lack of agreement between diagnostic instruments, emphasizing the need for clarity in assessing sarcopenia to improve identification and management in diverse populations.
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(1) Background: Metabolic syndrome (MSy) is defined by a constellation of interconnected physiological, biochemical, clinical, and metabolic factors that directly increase the risk of cardiovascular disease. This systematic review with meta-analysis was conducted to assess the effects of whole-body vibration exercise (WBVE) in metabolic syndrome (MSy) individuals. (2) Methods: An electronic search in Pubmed, Embase, Scopus, Web of Science, ScienceDirect, PEDro, and CINAHL databases in December 2022 was performed.

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Article Synopsis
  • Mitochondrial issues and redox imbalance are linked to the development of fibromyalgia (FM), and previous studies suggest whole-body vibration training (WBVT) could help improve these problems in women with FM.
  • The study involved 40 women with FM who were split into two groups: one receiving WBVT and the other remaining untrained; their body composition and various blood markers were assessed before and after a 6-week period.
  • Results showed that after WBVT, women had increased irisin levels, reduced oxidative stress markers, and lower visceral fat compared to those who did not train, indicating improved body composition and cell health.*
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Certain cut-off points for sarcopenia screening and diagnosis are arbitrary and based on European populations, with normative references often obtained from healthy young adults. Although respiratory skeletal muscle strength tests represent low-cost clinical measures commonly performed in clinical practice by health professionals, a gap remains regarding whether respiratory skeletal muscle strength tests are adequate and sensitive measures for sarcopenia screening. This study aimed to verify the value of handgrip and respiratory muscle strength as possible discriminators to identify sarcopenia and to establish cut-off points for sarcopenia screening in community-dwelling, Brazilian women.

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(1) Background: This study investigated the effects of two 6-week whole-body vibration exercise (WBVE) protocols on body composition in patients with metabolic syndrome (MSy). Thirty-three patients were allocated to either the Fixed Frequency WBVE Group (FFG-WBVE) or the Variable Frequency WBVE Group (VFG-WBVE). (2) Methods: A side-alternating vibration platform was used and the patients remained in the semi-squat position on this platform.

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To investigate the efficacy of hip strengthening on pain, disability, and hip abductor strength in musculoskeletal conditions of the trunk and lower limbs, we searched eight databases for randomized controlled trials up to 8 March 2022 with no date or language restrictions. Random-effect models estimated mean differences (MDs) with 95% confidence intervals (CIs), and the quality of evidence was assessed using the GRADE approach. Very low quality evidence suggested short-term effects (≤3 months) of hip strengthening on pain intensity (MD of 4.

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Patients with Chagas disease have reduced health-related quality of life (HRQoL). Hence, we aimed to identify the factors that mostly affected their HRQoL. This was a systematic review of qualitative studies.

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