Effect of Melatonin as an Antioxidant Drug to Reverse Hepatic Steatosis: Experimental Model.

Introduction: The hepatic steatosis of the nonalcoholic origin or NAFLD is increasing at present, particularly in Western countries, parallel to the increase in obesity, constituting one of the most prevalent hepatic processes in the Western society. Melatonin has been successfully tested in experimental models in mice as a drug capable of reversing steatosis. The effect of melatonin on fat metabolism can be summarized as a decrease in lipid peroxidation and a decrease in oxidative stress, biochemical phenomena intimately related to fat deposition in the hepatocyte.

Obesogenic Environment Case Study from a Food and Nutrition Security Perspective: Hermosillo City.

Obesity and certain nutritional deficiencies are global health problems that emerge in systems of interdependent individual biological and historical factors and social environmental determinants of health. Nutrition security is a framework that assumes stable access to sufficient innocuous and nutritious food (i.e.

Assessing the predictability of ANB, 1-NB, P-NB and 1-NA measurements on Steiner cephalometric analysis.

Objective: To evaluate, in the initial and final stages of corrective orthodontic treatment, the predictability of the ANB, 1-NB, PNB and 1-NA during case individualization, which considers the characteristics of the patient, professional experience and the mechanics to be used.

Methods: Ninety patients were selected at the State University of Londrina (UEL, Brazil), presenting Angle Class I and II malocclusions, treated with and without extraction of four premolars and divided into three groups: Horizontal, balanced and vertical. The cephalometric variables were evaluated in the initial, prognosis and final stages of treatment in order to observe the behavior of the estimates, or how they were higher or lower than the values obtained.

Small ablation zones created previous to saline infusion result in enlargement of the coagulated area during perfusion RF ablation: an ex vivo experimental study.

One of the strategies for enlarging coagulation zone dimensions during RF ablation of liver tumours is to infuse saline solutions into the tissue during ablation. The aim of this study was to evaluate experimentally whether the creation of a small coagulation adjacent to a bipolar RF applicator and prior to perfused RF ablation would allow enlargement of the coagulation zone. Thirty bipolar RF ablations (group A, n = 15; group B, n = 15) were performed in excised bovine livers.

Improved perfusion system for bipolar radiofrequency ablation of liver: preliminary findings from a computer modeling study.

Current systems for radiofrequency ablation of liver tumors are unable to consistently treat tumors larger than 3 cm in diameter with a single electrode in a single application. One of the strategies for enlarging coagulation zone dimensions is to infuse saline solutions into the tissue through the active electrodes. Nevertheless, the uncontrolled and undirected diffusion of boiling saline into the tissue has been associated with irregular coagulation zones and severe complications, mainly due to reflux of saline along the electrode path.