Publications by authors named "Ana C C Leandro"
Article Synopsis
- This study investigates the brain development of the marsupial Monodelphis domestica, highlighting its unique postnatal growth due to being born immature without placental support.
- Researchers used RNA-sequencing to analyze the expression of transporters and enzymes in the brains of newborn to juvenile Monodelphis, comparing the findings with data from developing eutherian rats.
- Results showed that Monodelphis has early limitations in drug entry into the brain, but compensates for the lack of placental protection by activating protective mechanisms during brain development.
