Objective: To know job satisfaction, work-family balance, sleep quality, and burnout in nursing staff after the introduction of the 12-h rotating shift in the emergency department of a tertiary hospital.
Method: Cross-sectional observational design carried out in February 2023 for the first collection (T1) and October 2023 for the second collection (T2) in emergency nursing staff. Sociodemographic data, work and family reconciliation, job satisfaction, degree of burnout, and sleep quality were collected.
Background: Von Hippel-Lindau (VHL) disease is a rare oncological disease with an incidence of 1:36,000, and is characterized by the growth of different types of tumors: hemangioblastomas in the central nervous system (CNS) and retina, renal carcinoma, pheochromocytomas, pancreatic serous cystadenoma, and endolymphatic sac tumors. These tumors do not express VHL protein (pVHL). pVHL ubiquitinates hypoxia inducible factor (HIF) protein for degradation by the proteasome; in the absence of VHL, HIF translocates to the nucleus to activate the expression of its target genes.
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