Publications by authors named "Ana Beatriz Villasenor-Altamirano"
Identification of key markers for the stages of nonalcoholic fatty liver disease: An integrated bioinformatics analysis and experimental validation.
Itayetzi Reyes-Avendaño Ana Beatriz Villaseñor-Altamirano Edilburga Reyes-Jimenez Juan Manuel Velazquez-Enriquez Rafael Baltiérrez-Hoyos
Dig Liver Dis
November 2024
Article Synopsis
- Researchers aimed to find biomarkers for early diagnosis of nonalcoholic fatty liver disease (NAFLD), focusing on the initial stages of steatosis (SS) and nonalcoholic steatohepatitis (NASH) using bioinformatics.
- A meta-analysis of transcriptomic data from patient biopsies helped identify 121 genes linked to SS and 402 to NASH, with key alterations related to cellular processes and cholesterol metabolism.
- The study highlighted specific candidate biomarkers (like ACSS2 and ANGPTL3) that could aid in the early screening and diagnosis of NAFLD in humans.