Publications by authors named "Ana Beatriz Dos Santos"

Prenatal iron (Fe) exposure has been associated with learning and cognitive impairments, which may be linked to oxidative stress resulting from elevated Fe levels and harm to the vulnerable brain. Drosophila melanogaster has contributed to our understanding of molecular mechanisms involved in neurological conditions. This study aims to explore Fe toxicity during D.

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Copper (Cu) is a naturally occurring metal with essential micronutrient properties. However, this metal might also pose increased adverse environmental and health risks due to industrial and agricultural activities. In Brazil, the maximum allowable concentration of Cu in drinking water is 2 mg/L.

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Mancozeb (MZ) is widely used as a fungicide in Brazil due to its effectiveness in combating fungal infections in plantations. However, its toxicity to non-target organisms, including aquatic organisms, has been reported in the literature. Recently, Brazilian legislation was updated to allow a concentration of 8 μg/L of MZ in drinking water (Ordinance GM/MS nº 888, of May 4, 2021).

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Article Synopsis
  • * The study observed that older flies showed reduced movement and balance, alongside increased oxidative stress markers, indicating ferroptosis is occurring in relation to aging.
  • * An increase in iron levels and a decrease in protective molecules like glutathione were found in older flies, suggesting that these factors contribute to age-related behavioral impairments and oxidative stress.
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