Publications by authors named "Ana Alice Amaral Ibiapina Parente"
Historically, all efforts against tuberculosis were focused on rapid diagnosis and effective treatment to break the chain of transmission of Mycobacterium tuberculosis. However, in the last few years, more and more evidence has been found on the dramatic consequences of the condition defined as post-tuberculosis lung disease (PTLD). Approximately one third of patients surviving pulmonary tuberculosis face considerable ongoing morbidities, including respiratory impairment, psychosocial challenges, and reduced health-related quality of life after treatment completion.
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- - The study investigated children and adolescents with tuberculosis (TB) who also had rheumatic diseases (RD) at a reference center in Rio de Janeiro between 1995 and 2022, revealing a higher occurrence of TB in this population compared to the general youth demographic.
- - Out of 15 patients studied, 53% were female, with a mean age of 7.1 years at RD diagnosis and 9.8 years at TB diagnosis, showcasing a variety of RD types and TB cases, including both pulmonary and extrapulmonary forms.
- - The findings highlight the necessity of timely TB diagnosis and treatment in RD patients undergoing immunosuppressive therapies, especially in countries like Brazil where TB prevalence is high. *
Article Synopsis
- The objective of the study was to review tuberculosis (TB) in children and adolescents with rheumatic diseases who are treated with biologic therapy.
- The research included 37 articles that analyzed data from 36,198 patients, finding 81 latent TB infections and low rates of active TB, primarily among those using anti-TNFα medications.
- The conclusions emphasized the importance of screening for latent TB before starting biologic therapy and treating those who test positive to prevent the progression to active TB disease.
Objective: The present study aimed to describe the clinical forms and the time taken to diagnose new tuberculosis cases and to statistically analyze the isolated and combined forms of the disease in children and adolescents treated at a university hospital in Rio de Janeiro during the first year of the COVID-19 pandemic in Brazil.
Methods: This was a cross-sectional study that used retrospective data on children (0-9 years old) and adolescents (10-18 years old) with pulmonary (PTB), extrapulmonary (EPTB), and combined tuberculosis (PTB + EPTB) followed up at the outpatient clinic from January 2019 to March 2021. Categorical data were analyzed by descriptive statistics and expressed as frequency and proportions.
Introduction: during functional respiratory assessments. The new digital peak flow meter (DPM) evaluates the forced expiratory volume in the first second (FEV) and PEF.
Objective: To compare lung function measurements using spirometry and DPM.
This prospective study describes the use of Gene-Xpert Ultra for the diagnosis of extrapulmonary tuberculosis (EPTB) in children and adolescents, in Rio de Janeiro, Brazil. Eighteen patients were studied; the final diagnosis of EPTB was established in 13 (72%). Gene-Xpert Ultra results showed detection in 10/13 (77%) of EPTB cases (7 of these 10 with trace-positive results).
View Article and Find Full Text PDFObjective: To evaluate the correlation between perception of dyspnea during a mild to moderate asthma attack using the Modified Borg Scale (MBS) and peak expiratory flow rate (PEFR).
Methods: This was a cross-sectional study conducted with children and adolescents who sought a pediatric emergency service due to an asthma attack. Data were collected from July 2005 to June 2006.