Focus on podocytes: diabetic kidney disease and renal fibrosis - a global bibliometric analysis (2000-2024).

Background: Diabetic kidney disease (DKD) is a common pathway to End-stage renal disease (ESRD). Podocytes are crucial due to their dual barrier functions in kidney diseases. Their role in renal fibrosis and DKD regulatory mechanisms is increasingly studied.

[Dao-di herbs pharmacology and new ideas of Dao-di herbs standard construction].

Guided by the basic theory of traditional Chinese medicine and using modern scientific methods, Dao-di herbs pharmacology studies the nature, performance, interaction with the body and its clinical application.It is a bridge between the basic research and clinical application of Dao-di herbs. It can objectively describe the law of efficacy of Dao-di herbs, scientifically explain the mechanism of efficacy of Dao-di herbs, explore and establish the standards and methods of Dao-di herbs based on biological effect and clinical efficacy, and provide scientific basis for the special properties, pharmacology and clinical value of Dao-di herbs.

[Generalized science of Chinese material medica-from preventive treatment of disease to Chinese medicine health industry].

Based on the systematic summary of the results of the fourth general survey of traditional Chinese medicine resources, the cultivation of large varieties of Chinese material medica and the latest research on health industrial development, the novel concepts and scientific connotations of generalized science of Chinese material medica are put forward, and the basic ideas and methods of a new Chinese medicine academic system, the cultivation system of large varieties of Chinese medicinal materials and the application system of the large health industry are constructed. This kind of generalized science of Chinese material medica, rooted in the traditional Chinese culture and the theory of "preventive treatment of disease", can avoid the narrow prospect induced by the increasing specialization and refinement of knowledge of science of Chinese material medica. It will play an important role in the modernization, industrialization, internationalization of traditional Chinese medicine.

[A Surface Plasmon Micro-Ring Sensor Suitable for Humidity Sensing].

Temperature is a very important parameter in scientific research, production and life. Almost all the properties of materials are related to temperature. The precise measurement of the temperature is a very important task, so the temperature sensor is widely used as a core part in the temperature measuring instrument.

[Pharmacokinetics and relative bioavailability of THC and THC-solid dispersion orally to mice at single dose].

To establish a fast sensitive, reproducible LC-MS/MS method to study pharmacokinetic properties of THC, and compare relative bioavailability of THC and its solid dispersion in mice. 200 mice were divided randomly into two groups, and administered orally with THC and THC-solid dispersion after fasting (calculate on THC:400 mg x kg(-1)), used HPLC-MS/MS method to determine the THC concentration of each period at the following times: baseline ( predose ), 15, 30, 45 min, 1, 1.5, 2, 3, 4, 6, 24 h after dosing.

[Quantitative analysis of volatile oils and isoimperatorin in rhizoma et Radix notopterygii].

Objective: To establish scientific and efficient quality control standard of Rhizoma et Radix Notopterygii through two quantitative parameters.

Method: The contents of isoimperatorin and volatile oils in 29 commercial samples from 22 localities of Rhizoma et Radix Notopterygii were determined by HPLC and the method in the pharmacopoeia respectively. The data were statistically analyzed.

[Studies on the preparation technology of beta-cyclodextrin inclusion compound for chuanxiong volatile oil extracted with CO2 supercritical fluid].

Objective: To explore the preparation technology of beta-cyclodextrin inclusion compound for chuanxiong volatile oil.

Method: Orthogonal test was used to evaluate the influence of the 4 factors, including the proportion of volatile oil to beta-cyclodextrin, the mode of mixing, inclusion temperature and mixing time.

Result: The best inclusion condition is the proportion of volatile oil to beta-cyclodextrin 1:9, the mode of mixing grinding, inclusion temperature 60 degrees C and inclusion time 90 min.