Flagellin from Enhances the Immune Response of Fused F18 from Enterotoxigenic .

F18 plays an important role in helping Enterotoxigenic (ETEC) binds to specific receptors on small intestinal enterocytes, followed by secreting of toxins causing diarrhea in post-weaning piglets (post-weaning diarrhea, PWD). However, the F18 subunit vaccine is not sufficient to stimulate an immune response that can protect weaning pigs from F18-positive ETEC (F18ETEC). Recently, a body of evidence shows that flagellin protein (FliC) helps to increase the immunity of fused proteins.