Publications by authors named "An-Jie Guo"
World J Clin Oncol
August 2024
Article Synopsis
- Immune checkpoint inhibitors (ICIs) are crucial immunotherapy drugs for cancer, but their increased use has led to a rise in immune-related adverse events (irAEs), impacting treatment effectiveness and patient survival.
- Current tests can identify specific organ damage but struggle to differentiate irAEs from infections or other immune disorders, highlighting the need for reliable biomarkers for irAE prediction or diagnosis.
- This review summarizes major irAEs, explores existing biomarker studies, and discusses advanced techniques like machine learning and gut microbiota profiling to find new biomarkers, while also explaining the mechanisms behind irAEs for better management strategies.
