2D monolayer electrocatalysts for CO electroreduction.

The electrocatalytic carbon dioxide reduction reaction (CORR) is an attractive method for converting atmospheric CO into value-added chemicals and fuels. In order to overcome the low efficiency and durability that hinder its practical application, a significant amount of research has been dedicated to designing novel catalysts at the nanoscale and even the atomic scale. Two-dimensional (2D) monolayer materials inherit the merits of both 2D materials and single-atom materials.

Evolutionary diversification and succession of soil huge phages in glacier foreland.

Background: Huge phages (genome size ≥ 200 kb) have been detected in diverse habitats worldwide, infecting a variety of prokaryotes. However, their evolution and adaptation strategy in soils remain poorly understood due to the scarcity of soil-derived genomes.

Results: Here, we conduct a size-fractioned (< 0.

College students' entrepreneurship education path and management strategy of start-up enterprises using causal attribution theory.

The current social entrepreneurship situation is not ideal. This study aims to enhance the effectiveness of college students' entrepreneurship education and improve the safety factor of start-up enterprises. Firstly, the current situation of college students' entrepreneurship education is studied through questionnaires and literature review.

Nest Site Selection by Green Sea Turtles () and Implications for Conservation on Qilianyu, Xisha Islands, South China Sea.

The green sea turtle () is the only sea turtle species that breeds in China, and the largest remaining nesting grounds for green sea turtles in Chinese waters is found on the Qilianyu atoll of the Xisha Islands. Nesting site selection is particularly important for egg survival, and understanding the microhabitat characteristics of green sea turtle nesting sites is crucial for delineating priority conservation areas for nesting grounds. In this study, we aimed to examine the role of several microhabitat ecological factors in the selection of nesting sites and the success of nesting.

Perceived problems associated with perioperative blood product preparation.

Timely blood product preparation is important for patients undergoing surgery with a high risk of blood loss. However, in circumstances where no blood refrigerators exist in the operating room theatre complex, numerous potential problem sources during blood product preparation may lead to delays, and tense interpersonal interactions between anaesthesia and blood bank personnel can ensue. To evaluate this at our institution, an anonymous online survey was sent to anaesthesia providers and blood bank technologists.

Photosynthesis-Inspired NIR-Triggered Fe₃O₄@MoS₂ Core-Shell Nanozyme for Promoting MRSA-Infected Diabetic Wound Healing.

Bacterial infections can lead to severe medical complications, including major medical incidents and even death, posing a significant challenge in clinical trauma repair. Consequently, the development of new, efficient, and non-resistant antimicrobial agents has become a priority for medical practitioners. In this study, a stepwise hydrothermal reaction strategy is utilized to prepare FeO@MoS core-shell nanoparticles (NPs) with photosynthesis-like activity for the treatment of bacterial infections.

Enhancing open-circuit voltage in FAPbI perovskite solar cells self-formation of coherent buried interface FAPbICl.

The interfaces between the perovskite and charge-transporting layers typically exhibit high defect concentrations, which are the primary cause of open-circuit voltage loss. Passivating the interface between the perovskite and electron-transporting layer is particularly challenging due to the dissolution of surface treatment agents during the perovskite coating. In this study, a coherent FAPbICl buried interface was simultaneously formed during the preparation of FAPbI.

Comparison of the effectiveness and safety of GLP-1 receptor agonists for type 2 diabetes mellitus patients with overweight/obesity: A systematic review and network meta-analysis.

Objective: To evaluate the effectiveness and safety of different Glucagon-like peptide-1 receptor agonists (GLP-1RAs) in treating type 2 diabetes mellitus (T2DM) with overweight/obesity using a systematic review and network meta-analysis.

Methods: We searched PubMed, Embase, Cochrane Library, and Web of Science up to December 20, 2024, for randomized controlled trials (RCTs) involving T2DM patients with overweight/obesity treated with GLP-1RAs, with the control group receiving either a placebo or another GLP-1RA. We conducted a network meta-analysis assessed evidence using CINeMA.

Correction: Effects of nitrogen, phosphorus and potassium formula fertilization on the yield and berry quality of blueberry.

[This corrects the article DOI: 10.1371/journal.pone.

Annexins: central regulators of plant growth and stress signaling.

Annexins are a family of multifunctional calcium-dependent and phospholipid-binding proteins that are widely distributed in the plant kingdom. They have a highly conserved evolutionary history that dates back to single-celled protists. Plant annexins, as soluble proteins, can flexibly bind to endomembranes and plasma membranes, exhibiting unique calcium-dependent and calcium-independent characteristics.

Protective effects of Notoginsenoside R2 on reducing lipid accumulation and mitochondrial dysfunction in diabetic nephropathy through regulation of c-Src.

Background: The treatment options to delay the progression of diabetic nephropathy (DN), a key contributor to chronic kidney disease (CKD), are urgently needed. Previous studies reported that traditional Chinese medicine Panax notoginseng (PNG) exerted beneficial effects on DN. However, the renoprotective effects of Notoginsenoside R2 (NR2), an active component of PNG, on DN have not been investigated.

Comparison of Jinzhen oral liquid and ambroxol hydrochloride and clenbuterol hydrochloride oral solution in the treatment of acute bronchitis in children: A multicenter, non-inferiority, prospective, randomized controlled trial.

The comparison between traditional Chinese medicine Jinzhen oral liquid (JZOL) and Western medicine in treating children with acute bronchitis (AB) showed encouraging outcomes. This trial evaluated the efficacy and safety of the JZOL for improving cough and expectoration in children with AB. 480 children were randomly assigned to take JZOL or ambroxol hydrochloride and clenbuterol hydrochloride oral solution for 7 days.

Impacts of genomic alterations on the efficacy of HER2-targeted antibody-drug conjugates in patients with metastatic breast cancer.

Background: HER2-targeted antibody-drug conjugates (ADCs) have revolutionized the treatment landscape of metastatic breast cancer. However, the efficacy of these therapies may be compromised by genomic alterations. Hence, this study aims to identify factors predicting sensitivity to HER2 ADC in metastatic breast cancer.

[A new nortriterpenoid from mastic].

Ten compounds were separated by various modern chromatographic methods from mastic. They were identified by HR-ESI-MS, IR, UV, NMR, quantum chemical calculation of NMR(qcc-NMR) and comparison with reported data in literature as 17β-hydroxy-28-norolean-18-en-3-one(1), 28-norolean-12,17-dien-3,11-dione(2), 28-norolean-16,18-dien-3-one(3),(24Z)-26-hydroxy-7,24-dientirucalla-3-one(4), masticadienonic acid(5)、masticadienolic acid(6)、erythrodiol(7), 3β,28-dihydroxyoleana-11,13(18)-diene(8), 3-oxo-olean-9(11),12-dien-28-oic acid(9), and 12-oleane-3,11-dione(10). Among them, compound 1 was a novel compound and compound 2 was a novel natural product.

High-Efficiency Intrinsically Thermoplastic Semiconducting Polymer with Excellent Strain-Tolerance Capacity for Flexible Ultra-Deep-Blue Polymer Light-Emitting Diodes.

Complex internal stresses that appear in flexible thin-film electronic devices under long-term deformation operation are associated with incompatible mechanical properties of the multiple layers, which potentially cause intralayer fracture and separation. These defects may result in device instability, performance loss, and failure. Herein, a thermoplastic functional strategy is proposed for manufacturing high-performance stretchable semiconducting polymers with excellent strain-tolerance capacities for flexible electronic devices.

Study of the SPL gene family and miR156-SPL module in Populus tomentosa: Potential roles in juvenile-to-adult phase transition and reproductive phase.

Populus tomentosa, a deciduous tree species distinguished by its significant economic and ecological value, enjoys a wide-ranging natural distribution. However, its long juvenile period severely restricts the advancement of breeding work. The SPL gene family, a distinctive class of transcription factors exclusive to the plant kingdom, is critical in various processes of plant growth and development.

Comprehensive analysis of the multi-rings mitochondrial genome of Populus tomentosa.

Background: Populus tomentosa, known as Chinese white poplar, is indigenous and distributed across large areas of China, where it plays multiple important roles in forestry, agriculture, conservation, and urban horticulture. However, limited accessibility to the mitochondrial (mt) genome of P. tomentosa impedes phylogenetic and population genetic analyses and restricts functional gene research in Salicaceae family.

Facile Synthesis of a CuMoO Nanosheet Array for Electrochemical Reduction of Nitrite to Ammonia in Neutral Solution.

Electrochemical nitrite (NO) is a promising technology for NO removal and a sustainable method for generating valuable ammonia (NH), but this process is intricate and generates other byproducts. In this work, we propose a facile and low-cost method for the preparation of a CuMoO nanosheet array, which can serve as an efficient electrocatalyst for the reduction of NO to NH. The morphology of CuMoO can be adjusted by controlling the synthesis conditions.

Genomic Selection and WssGWAS of Sheep Body Weight and Milk Yield: Imputing Low-Coverage Sequencing Data with Similar Genetic Background Panels.

Low-coverage whole-genome sequencing (LcWGS), a cost-effective genotyping method, offers greater flexibility in variant detection than does single-nucleotide polymorphism (SNP) chips. However, to our knowledge, no studies have explored the application of LcWGS in sheep. This study aimed to evaluate the feasibility of implementing LcWGS and genotype imputation and assess their applicability in genomic studies of body weight and milk yield in sheep.

Research on a Lightweight Arrhythmia Classification Model Based on Knowledge Distillation for Wearable Single-Lead ECG Monitoring Systems.

Arrhythmias are among the diseases with high mortality rates worldwide, causing millions of deaths each year. This underscores the importance of real-time electrocardiogram (ECG) monitoring for timely heart disease diagnosis and intervention. Deep learning models, trained on ECG signals across twelve or more leads, are the predominant approach for automated arrhythmia detection in the AI-assisted medical field.

Protein aggregation behavior and structural characteristics in a lipoxygenase-linoleic acid-wheat gluten model system.

This study explores the synergistic effects of linoleic acid (LA) oxidation on the aggregation behavior and structural properties of wheat gluten (WG). Using lipoxygenase to induce LA oxidation, it was observed that this process significantly influenced WG's viscoelasticity and structural characteristics. Specifically, LA oxidation enhanced WG's viscoelastic properties while reducing its instantaneous elastic and recovery deformations.

New Insights into the Ion/Electron Transfer Mechanisms of LiMnO-Based Membrane Electrodes at Different Electron Fluxes.

Electrochemical Li extraction technology is a highly promising approach for Li extraction from salt lakes. To enhance its practical application, it is crucial to elucidate the ion/electron transfer mechanism under diverse process conditions particularly different electron fluxes. Different migration intermediate states demonstrate the distinct ion migration mechanisms inside the LiMnO lattice at different electron fluxes.

TangBi Formula for Painful Diabetic Distal Symmetric Polyneuropathy: A Multicenter, Randomized, Double-Blind, Placebo-Controlled and Parallel-Group Trial.

Objective: To determine whether the use of herbal medicines combined with conventional treatment is more effective than conventional medication alone in improving clinical symptoms in patients with diabetic distal symmetric polyneuropathy (DSPN).

Methods: This multicenter, placebo-controlled, double-blind, randomized controlled clinical trial recruited patients from 6 clinical centers in mainland China. A total of 188 patients were randomly assigned in a 1:1 ratio to the treatment group (Tangbi Formula plus methylcobalamin) and the control group (placebo plus methylcobalamin).

Anisotropic Plasmon Resonance in TiCT MXene Enables Site-Selective Plasmonic Catalysis.

The ever-growing interest in MXenes has been driven by their distinct electrical, thermal, mechanical, and optical properties. In this context, further revealing their physicochemical attributes remains the key frontier of MXene materials. Herein, we report the anisotropic localized surface plasmon resonance (LSPR) features in TiCT MXene as well as site-selective photocatalysis enabled by the photophysical anisotropy.