Serum syndecan-4 is associated with nonalcoholic fatty liver disease.

Objectives: The accelerated shedding of extracellular domains of syndecan-4 (SDC4) is associated with central obesity and insulin resistance, while the association between serum SDC4 and nonalcoholic fatty liver disease (NAFLD) is unknown. We aimed to examine the association between SDC4 and NAFLD.

Methods: Adults undergoing a health examination from 1 June 2019 to 31 December 2019 were enrolled.