Publications by authors named "An Ji"

Background: The unilateral absence of a pulmonary artery (UAPA) is a very rare congenital pulmonary vascular malformation. Since the first case was reported in 1868, the overall incidence of UAPA has been at a level of 1/300,000 - 1,200,000. Isolated UAPA without other cardiac anomalies is rare.

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  • The study analyzed the effectiveness and safety of telemedicine for chronic diseases in South Korea during the COVID-19 pandemic, focusing on a temporary telemedicine policy.
  • It utilized national health insurance claims data from before and after the policy's implementation, comparing patients who used telemedicine with those who did not across four chronic diseases.
  • Results indicated that telemedicine improved medication adherence for hypertension and diabetes without increasing hospital admissions, while those who did not use telemedicine faced higher admission rates.
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In the post-pandemic era, interest in on-site technologies capable of rapidly and accurately diagnosing viral or bacterial pathogens has significantly increased. Advances in functional nanomaterials and bioengineering have propelled the progress of point-of-care (POC) sensors, enhancing their speed, specificity, sensitivity, affordability, ease of use, and accuracy. Notably, biosensors that utilize surface-enhanced Raman scattering (SERS) technology have revolutionized the rapid and sensitive diagnosis of biomarkers in pathogenic infections.

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Background: Few studies have been conducted on the prevention of bile reflux in gastric cancer patients who have undergone gastrectomy. The aim of this study was to evaluate the efficacy and safety of ursodeoxycholic acid (UDCA) in preventing bile reflux after gastrectomy in patients with gastric cancer.

Methods: This study was a secondary analysis of the PEGASUS-D trial, a randomized, double-blind, placebo-controlled clinical trial.

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  • Precision medicine requires reliable tools for personalized therapy, and this study tested the feasibility of the single patient classifier (SPC) test for stage II-III gastric cancer patients.
  • A multicenter study with 237 patients showed that 99.5% of SPC test results were delivered on time before choosing postoperative treatments, with a median delivery time of 4 days.
  • The results indicated significant differences in 3-year disease-free survival rates among the risk groups identified by the SPC test, supporting its potential for improving treatment decisions.
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Backgrounds/aims: This meta-analysis examined whether preoperative vibration-controlled transient elastography (VCTE) can predict postoperative complications and recurrence in patients undergoing hepatic resection for hepatocellular carcinoma (HCC).

Methods: A systematic literature search was conducted using Ovid-Medline, EMBASE, Cochrane, and KoreaMed databases. Out of 431 individual studies, thirteen published between 2008 and 2022 were included.

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  • - Sentinel node navigation (SNN) is effective for stomach-preserving surgery in early gastric cancer but has technical challenges in practice.
  • - A study analyzed data from the SENORITA trial, evaluating the effectiveness of regional lymphadenectomy without SNN on 237 patients, focusing on lymph node metastasis in relation to tumor location.
  • - Results indicated that while SNN showed higher sensitivity and negative predictive values for detecting metastasis compared to regional lymphadenectomy, completely omitting SNN in surgery was deemed insufficient and not recommended.
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  • Lymphoepithelioma-like carcinoma (LELC) is a rare form of early gastric cancer, characterized by younger patients and a greater occurrence of tumors located in the upper stomach.
  • Despite having a higher rate of deep submucosal invasion compared to well or moderately differentiated gastric cancers, LELC shows lower rates of lymphatic invasion and lymph node metastasis (LNM).
  • The study suggests that endoscopic submucosal dissection could be an effective treatment option for early-stage LELC, particularly for tumors limited to the mucosa or shallow submucosa due to the low risk of metastasis.
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  • - The Fibrosis-4 index (FIB-4) is a noninvasive test used to assess advanced liver fibrosis (AF) in patients with nonalcoholic fatty liver disease (NAFLD), though its effectiveness in those with type 2 diabetes mellitus (T2DM) is debated due to high AF rates in this group.
  • - A meta-analysis of 12 studies involving 5,624 NAFLD patients with T2DM revealed that FIB-4 has moderate sensitivity and specificity, particularly showing better performance at high cutoffs (high specificity but lower sensitivity).
  • - While FIB-4 can be useful for diagnosing AF, the current evidence is limited and varied, suggesting a need for more research to
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  • The SENORITA trial aimed to evaluate the quality of life (QoL) and nutritional outcomes of patients undergoing two types of surgeries: laparoscopic sentinel node navigation surgery (LSNNS) and laparoscopic standard gastrectomy (LSG).
  • The objective was to compare long-term QoL and nutritional outcomes between patients who had stomach-preserving surgery and those who underwent standard gastrectomy, as well as to identify factors affecting QoL in the stomach-preserving group.
  • The analysis included 194 patients who underwent stomach-preserving surgery and 257 who had standard gastrectomy, with findings indicating that the stomach-preserving group experienced better QoL scores three months post-surgery.
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Root biomass and distribution are influenced by abiotic factors, such as topography and soil physicochemical properties, determining belowground productivity. Hence, we investigated the variation in root biomass and vertical root distribution based on the topography, soil physicochemical properties, and tree influence index, and their relationships, across soil depths (0-10 cm, 10-20 cm, and 20-30 cm) and topographical gradients in a warm-temperate forest in Mt. Duryun, Republic of Korea.

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Background And Aims: When treating undifferentiated-type early gastric cancer (UD-EGC) that is limited to the mucosa (clinically T1a), endoscopic submucosal dissection (ESD) can be considered if the tumor is 2 cm or less and is not ulcerated. However, there is insufficient evidence to determine the relationships between tumor size and oncological safety of ESD in UD-EGC.

Methods: The pathology reports of Korean patients who were diagnosed with UD-EGC (n = 5286) were retrospectively reviewed.

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  • Surgery combined with chemotherapy is the standard treatment for locally advanced gastric cancer (GC) and gastroesophageal junction cancer (GEJC), but outcomes are often poor, especially in specific genetic subtypes like dMMR/MSI-high.* -
  • Analysis from several clinical trials shows that patients with MSI-high tumors generally have better survival rates than those with MSS/MSI-low tumors, and that female patients with MSS/MSI-low tumors tend to live longer than their male counterparts.* -
  • The study emphasizes that sex can influence the effectiveness of treatments for both MSI-high and MSS/MSI-low non-metastatic GC/GEJC, with surprisingly higher chemotherapy risks noted in females with MSI-high cancers.*
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Objective: This study aimed to investigate the association between gaming time and problematic game use (PGU) within a large sample of Korean male gamers and to examine the potential moderating effects of loneliness, living alone, and household size.

Methods: This study employed data from 743 male gamers from the National Mental Health Survey 2021, a nationally representative survey of mental illness conducted in South Korea. Self-reported data on the average gaming time per day, severity of PGU, loneliness, living alone, and household size were used.

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The subtype diagnosis and severity classification of mood disorder have been made through the judgment of verified assistance tools and psychiatrists. Recently, however, many studies have been conducted using biomarker data collected from subjects to assist in diagnosis, and most studies use heart rate variability (HRV) data collected to understand the balance of the autonomic nervous system on statistical analysis methods to perform classification through statistical analysis. In this research, three mood disorder severity or subtype classification algorithms are presented through multimodal analysis of data on the collected heart-related data variables and hidden features from the variables of time and frequency domain of HRV.

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Urbanization and associated forest conversions have given rise to a continuum of native (forest fragments) and modified (artificial grasslands and perennial ecosystems) land-use types. However, little is known about how these shifts affect soil and fine-root compartments that are critical to a functioning carbon and nutrient circulation system. In this study, soil physicochemical properties, fine-root mass, and vertical distribution patterns were investigated in four representative urban land-use types: grassland (ZJ), perennial agroecosystem (MP), broadleaf deciduous forest patch (QA), and coniferous evergreen forest patch (PD).

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It is crucial to evaluate the effects of thinning on litterfall production, soil chemical properties, and fine root dynamics when implementing thinning as a silvilcultural technique to enhance tree growth and timber yield in plantations. Thus, we determined the 10-year effects (2007-2017) of different thinning intensities on litterfall production, soil chemical properties, and fine root biomass and necromass within a plantation in South Korea. The soil chemical parameters and fine root biomass and necromass were also compared across three soil depths (0-10, 10-20, and 20-30 cm).

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Regular physical activity (PA) has been suggested as effective disease preventable strategies for Parkinson's disease (PD). Depression often precedes PD but whether PA also would reduce the risk of PD in patients with depression has not been known. The aim of study is to examine the association of regular PA with risk of PD among patients with depressive disorder.

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Tinnitus is the perception of abnormal sounds in the ears or head without external auditory stimulation. While classical test theory is often used in tinnitus questionnaire development, it has limitations in assessing item characteristics. Item response theory (IRT) offers more precise individual ability estimations and identifies key and less important items, making it superior for reliable measurement tools.

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Timely and accurate interpretation of chest radiographs obtained to evaluate endotracheal tube (ETT) position is important for facilitating prompt adjustment if needed. The purpose of our study was to evaluate the performance of a deep learning (DL)-based artificial intelligence (AI) system for detecting ETT presence and position on chest radiographs in three patient samples from two different institutions. This retrospective study included 539 chest radiographs obtained immediately after ETT insertion from January 1 to March 31, 2020, in 505 patients (293 men, 212 women; mean age, 63 years) from institution A (sample A); 637 chest radiographs obtained from January 1 to January 3, 2020, in 302 patients (157 men, 145 women; mean age, 66 years) in the ICU (with or without an ETT) from institution A (sample B); and 546 chest radiographs obtained from January 1 to January 20, 2020, in 83 patients (54 men, 29 women; mean age, 70 years) in the ICU (with or without an ETT) from institution B (sample C).

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Background And Objectives: While variabilities in metabolic parameters (METv) have been linked to adverse health outcomes in type 2 DM, their association with depression is yet to be studied. This research aimed to investigate the association between METv and depressive disorder in patients with type 2 DM.

Methods: The study involved a nationwide cohort of 1,119,631 type 2 DM patients who had undergone three or more serial health examinations between 2005 and 2012.

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Diabetes is a prevalent and debilitating metabolic disorder affecting a large population worldwide. The condition is characterized by insulin resistance and impaired function of pancreatic β-cells, leading to elevated blood glucose levels. In this study, the antidiabetic effects of extract (EAE) on zebrafish with damaged pancreatic islets caused by insulin resistance were investigated.

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Background: Clinical benefits of the meso-jejunal lymph node (MJLN) dissection in remnant gastric cancer (RGC) patients have not been fully established. Hence, in this retrospective study, we evaluated the survival benefit of MJLN dissection and prognostic significance of MJLN metastasis in RGC patients who underwent gastrojejunostomy reconstruction after their initial gastrectomy.

Methods: We retrospectively reviewed 391 patients who underwent surgery for RGC at our institution between 1996 and 2019.

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