Publications by authors named "Amy Suk Wai Ho"
Article Synopsis
- Temozolomide (TMZ) is commonly used to treat glioblastoma multiforme (GBM), and this study explored the combined effects of rutin, a flavonoid with anticancer properties, on enhancing TMZ's efficacy.
- In cell viability tests, rutin showed low toxicity on its own but boosted TMZ's effectiveness in fighting GBM cells in a dose-dependent manner.
- Animal studies confirmed that combining rutin with TMZ resulted in significantly smaller tumor sizes, and the mechanisms involved indicated that rutin inhibits a protective process promoted by TMZ, leading to increased cancer cell death.
