The relationship between forgiveness and borderline personality symptomatology.

The relationship between forgiveness and borderline personality symptomatology has been rarely studied. Using a consecutive cross-sectional sample of 307 internal medicine outpatients and a survey methodology, we examined correlations between the Forgiveness Scale and borderline personality symptomatology as measured by the borderline personality disorder scale of the Personality Diagnostic Questionnaire-4 and the Self-Harm Inventory. Numerous forgiveness subscales as well as the composite Forgiveness Scale score demonstrated statistically significant relationships with both measures for borderline personality symptomatology, such that individuals with this personality pathology demonstrated lower scores on these forgiveness subscales.

Bullying in childhood and religious/spiritual status in adulthood among internal medicine outpatients.

Background: Bullying in childhood is ubiquitous and associated with a number of identified negative outcomes in both childhood and adulthood. However, the relationship between being bullied in childhood and religious/spiritual status in adulthood has never been explored.

Method: Using a cross-sectional sample of 324 consecutive internal medicine outpatients and a survey methodology, we examined relationships between 'When you were growing up, were you ever a victim of bullying?' and (1) self-perceived extent of religiosity/spirituality and (2) religiosity/spirituality as assessed by scores on the Functional Assessment of Chronic Illness Therapy-Spiritual Well-Being Scale (FACIT-Sp-12).

Perceptions of parental caretaking in childhood and religiosity/spirituality status in adulthood.

Relationships between parental caretaking quality in childhood and religiosity/spirituality in adulthood, which are the focus of the present study, have undergone limited study. Using a cross-sectional sample of consecutive internal medicine outpatients, we examined in 308 participants three aspects of their parenting experience (i.e.

Abuse in childhood and religious/spiritual status in adulthood among internal medicine outpatients.

The relationship between abuse in childhood and religiosity/spirituality status in adulthood has been previously studied, but not in a medical sample or with the current study measure. Using a cross-sectional consecutive sample of 317 internal medicine outpatients, we asked participants, "As a child, were you the victim of either physical or sexual abuse?," and assessed religiosity/spirituality status with the Functional Assessment of Chronic Illness Therapy-Spiritual Well-Being Scale (FACIT-Sp-12). We found that among the cohort with abuse in childhood, seven of twelve scales as well as the overall FACIT-Sp-12 score demonstrated statistically significant differences, with abused participants consistently evidencing lower religiosity/spirituality scores.

Religion/spirituality status and borderline personality symptomatology among outpatients in an internal medicine clinic.

Objective: This study was designed to assess religion/spirituality (RS) status over the preceding 12 months in relationship to borderline personality symptomatology status.

Methods: Using a cross-sectional consecutive sample of internal medicine outpatients and a self-report survey methodology, we examined RS using the 12-item Functional Assessment of Chronic Illness Therapy-Spiritual Well-Being Scale (FACIT-Sp-12), and borderline personality symptomatology using two self-report measures, the borderline personality scale of the Personality Diagnostic Questionnaire-4 and the Self-Harm Inventory.

Results: The majority of FACIT-Sp-12 scales as well as the overall FACIT-Sp-12 score demonstrated an inverse relationship with scores on the individual measures for borderline personality symptomatology as well as a combined measure of such symptoms (individuals who scored positively on both measures).

YPEL3, a p53-regulated gene that induces cellular senescence.

Cellular senescence, the limited ability of cultured normal cells to divide, can result from cellular damage triggered through oncogene activation (premature senescence) or the loss of telomeres following successive rounds of DNA replication (replicative senescence). Although both processes require a functional p53 signaling pathway, relevant downstream p53 targets have been difficult to identify. Discovery of senescence activators is important because induction of tumor cell senescence may represent a therapeutic approach for the treatment of cancer.