Synopsis of recent research by authors named "Amy L Garrett"
- Amy L Garrett's recent research focuses on understanding the molecular and environmental drivers of metastatic breast cancer, utilizing multiomics approaches to analyze tissue samples and identify key factors associated with metastasis, particularly from the AURORA US network.
- She has explored novel treatment strategies for triple-negative breast cancer (TNBC), examining the effectiveness of a cyclophosphamide priming dose prior to pembrolizumab to enhance immune checkpoint inhibition and target the tumor microenvironment.
- Additionally, her work includes developing advanced methods for tracking plasma DNA mutations in estrogen receptor-positive metastatic breast cancer, providing insights into therapeutic responses and contributing to a better understanding of breast cancer metastasis mechanisms through integrated DNA and RNA sequencing.